Predictors of seizure related injuries in adult patients with epilepsy in Colombia: a case-control study - Orozco-Hernandez JP, Quintero-Moreno JF, Duque-Salazar C, Gil-Restrepo A, William-Martinez J, Lizcano-Meneses A, Carmona-Villada H.

AIM: To identify predictors of seizure related injuries in adult patients with epilepsy in Colombia. SUBJECTS AND METHODS: Case-control study. Patients with a diagnosis of epilepsy aged 16 years and older who attended the Neurocentro epilepsy cente...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

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Publication date: Available online 23 April 2019Source: NeuroImageAuthor(s): Hossein Sohanian Haghighi, Amir H.D. MarkaziAbstractSpike and wave discharges are the main electrographic characteristic of a number of epileptic brain disorders including childhood absence epilepsy and photosensitive epilepsy. The basic dynamic mechanism that underlies the occurrence of these abnormal electrical patterns in the brain is not well understood. The current paper aims to provide a dynamic explanation for features and generation mechanism of spike and wave discharges in the brain. The main proposition of this study is that epileptic se...
Source: NeuroImage - Category: Neuroscience Source Type: research
AbstractObjectivesTo document the prevalence of hypovitaminosis-D in children with intellectual and movement disorders and to identify the risk factors in vitamin D deficient children.MethodsThis is a cross-sectional study on 90 children with neurodevelopmental disabilities. The prevalence of hypovitaminosis-D and the risk factors such as sun exposure, age-appropriate mobility, diet, skin color and anti-epileptic medications were examined in children with cognitive disorders and movement disorders.ResultsThe mean serum vitamin D level in children with cognitive disability (n  = 46) was found to be 26.7&thinsp...
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Xu Zhao1, Zhi-qiang Zhou2, Ying Xiong1, Xu Chen3, Ke Xu4, Juan Li1, Ying Hu1, Xiao-long Peng1 and Wen-zhen Zhu1* 1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 2Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 3Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 4Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science an...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusions: Lifestyle factors, such as physical activity, sleep, and social activity appear to be associated with cognitive function among older people. Physical activity and appropriate durations of sleep and conversation are important for cognitive function. Introduction Dementia is a major public health issue worldwide, with a serious burden for patients, caregivers, and society, as well as substantial economic impacts (1). Although the prevalence of late-life cognitive impairment and dementia are expected to increase in future, effective disease-modifying treatments are currently unavailable. Therefore, unders...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
In conclusion, while rs-fMRI use in clinical neuroradiology practice is limited, enthusiasm appears to be quite high and there are several possible avenues in which further research and development may facilitate its penetration into clinical practice. Introduction Techniques for quantifying spatial and temporal brain activity have developed rapidly since the first demonstrations that MRI could be used to measure modulations in blood oxygen level dependent (BOLD) tissue contrast (1). The observation that MRI could be used to monitor temporally correlated low-frequency activity fluctuations in spatially remote brain a...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion Despite the above limitations, this systematic review supports a view that modulation of sympathetic activity using GSR biofeedback represents a promising new therapeutic tool for management of seizures in patients with epilepsy. For future clinical trials, important elements to be considered include size of patient population, seizure type, double-blinding, inclusion of an appropriate control group, and robust randomization methods. Ethics Statement We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidel...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
For the first time, children in the United States will have a non-drug option for treating attention deficit hyperactivity disorder (ADHD). The FDA just cleared the Monarch external Trigeminal Nerve Stimulation (eTNS) System from NeuroSigma, a Los An...
Source: Medgadget - Category: Medical Devices Authors: Tags: Neurology Pediatrics Psychiatry Rehab Source Type: blogs
Publication date: June 2019Source: Epilepsy &Behavior, Volume 95Author(s): Suzanne O. Nolan, Samantha L. Hodges, Siena M. Condon, Ilyasah D.A. Muhammed, Lindsay A. Tomac, Matthew S. Binder, Conner D. Reynolds, Joaquin N. LugoAbstractThere is increasing evidence that seizures during early development can impact ultrasonic vocalizations (USVs) emitted from neonatal mice. However, most of the effects of early-life seizures have been reported using chemoconvulsants that produce continuous seizures (status epilepticus). In the present study, we evaluated the impact of different seizure frequency loads during early-life voca...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
ConclusionsThe present study indicates that IDD occurs in high frequency in PWE with a substantial overlap of IDD with depressive and anxiety disorders. The study highlights the importance of the observer-based systematic approach for diagnosing IDD and the usage of operationalized diagnostic criteria for psychiatric comorbidities in PWE. Future research should be directed at validating whether IDD is nosologically independent of other psychiatric conditions.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Conclusion: We screened 12 receptor tyrosine kinases inhibitors, and EGFR/ErbB-2 and cFMS inhibitors were identified as novel antiepileptic compounds. Significance: This epilepsy-on-a-chip system provides the means for rapid dissection of complex signaling pathways in epileptogenesis, paving the way for high-throughput antiepileptic drug discovery.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
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