Effects of tiotropium bromide on airway hyperresponsiveness and inflammation in mice exposed to organic dust

Conclusions Tiotropium decreased the OD-induced increase of specific cytokines without influencing the OD-induced increase of airway responsiveness and neutrophil infiltration into the lungs. We conclude that the cholinergic pathway contributes to the pro-inflammatory effects caused by inhalation of OD from pig barns.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research