Enantioselective synthesis of novel pyrano[3,2-c]chromene derivatives as AChE inhibitors via an organocatalytic domino reaction

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02794J, PaperJie Zheng, Ming He, Baohua Xie, Lu Yang, Zhiye Hu, Haibing Zhou, Chune Dong A series of optical active pyrano[3,2-c]chromenes have been synthesized through asymmetric domino reaction of 4-hydroxy-2H-chromen-2-ones with malononitriles. The targeted molecules were obtained in excellent yields and enantioselectivities (up to 94%... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research