From ASH: No benefit to XRT after RCHOP in Stage I-II DLBCL

https://www.ashclinicalnews.org/news/radiotherapy-necessary-treating-dlbcl-r-chop/ This was a non-inferiority trial for non-bulky Stage I-II DLBCL treated with RCHOP +/- XRT. No statistically significant difference in overall survival at 5 years. Several issues come to mind: 1. Not even the most vigorous defender of radiation in DLBCL would suggest that XRT represents an 8% OS advantage relative to R-CHOP alone. 2. Why 40 Gy? 30 Gy should be sufficient for non-bulky... From ASH: No benefit to XRT after RCHOP in Stage I-II DLBCL
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