From ASH: No benefit to XRT after RCHOP in Stage I-II DLBCL
https://www.ashclinicalnews.org/news/radiotherapy-necessary-treating-dlbcl-r-chop/
This was a non-inferiority trial for non-bulky Stage I-II DLBCL treated with RCHOP +/- XRT. No statistically significant difference in overall survival at 5 years.
Several issues come to mind:
1. Not even the most vigorous defender of radiation in DLBCL would suggest that XRT represents an 8% OS advantage relative to R-CHOP alone.
2. Why 40 Gy? 30 Gy should be sufficient for non-bulky...
From ASH: No benefit to XRT after RCHOP in Stage I-II DLBCL
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Gfunk6 Source Type: forums