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Cadila gets USFDA nod for generic drug to treat Parkinson's

The Ahmedabad-based firm also received final approval from the USFDA to market Nitrofurantoin Capsules USP, used for treating acute uncomplicated urinary tract infections, in the US market.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news

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ConclusionsOsteoporotic fractures led to amount of medical complications, which significantly increased patients ’ economic burden. Complications correlate to various factors such as patients’ disease history.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research
This study is registered at ClinicalTrials.gov, number NCT02035553. Findings Between Jan 16, 2014, and Oct 27, 2016, 345 participants across 133 nursing homes were screened, of whom 181 were randomly assigned treatment (n=90 pimavanserin and n=91 placebo). 178 participants were included in the modified intention-to-treat population. Mean total baseline NPI–NH psychosis scores were 9·5 (SD 4·8) for the pimavanserin group and 10·0 (5·6) for the placebo group. Mean change in the NPI–NH psychosis score at week 6 was −3·76 points (SE 0·65) for pimavanserin and −1...
Source: The Lancet Neurology - Category: Neurology Source Type: research
Conclusions: The findings highlight PD as a multisystem neurodegenerative disorder, and this information is crucial for creating strategies to better prevent and manage PD complications.Neuroepidemiology
Source: Neuroepidemiology - Category: Epidemiology Source Type: research
CONCLUSIONS: There is little or no increased suicide mortality following acute admissions for most physical illnesses. Much of the increased suicide mortality relates to gastrointestinal disorders that are often alcohol related or specific chronic conditions, which may be linked to side effects from certain therapeutic medications. Acute hospital admissions for physical illnesses may therefore provide an opportunity for targeted suicide prevention among people with certain conditions, particularly alcohol related disorders. PMID: 28714426 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
This article aims to provide an update on PD and explore the nurse's role in assessment and provision of safe and effective care for patients with PD in acute hospital settings. PMID: 28560917 [PubMed - in process]
Source: Nursing Older People - Category: Nursing Authors: Tags: Nurs Older People Source Type: research
Publication date: September 2016 Source:Journal of Clinical Neuroscience, Volume 31 Author(s): Abhimanyu Mahajan, Poojitha Balakrishnan, Achint Patel, Ioannis Konstantinidis, Dominic Nistal, Narender Annapureddy, Priti Poojary, Girish N. Nadkarni, Christos Sidiropoulos The total number of people living with Parkinson’s disease (PD) worldwide is expected to double by 2030. The risk factors for emergency department visits in PD patients have been described before, however, there is limited data on inpatient hospitalizations of PD patients. We derived our study cohort from the Nationwide Inpatient Sample (NIS...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Abstract BACKGROUND: Bullous pemphigoid (BP) is associated with significant disability and comorbid health disorders that may lead to or result from hospitalization. However, little is known about the inpatient burden and comorbidities of BP. METHODS: We analyzed data from the 2002-2012 National Inpatient Sample, including a representative 20% sample of all hospitalizations in the US (n=72,108,077 adults). RESULTS: The prevalences of hospitalization for BP increased from 25.84 to 32.60 cases per million inpatients from 2002 to 2012. In multivariate logistic regression models with stepwise selection, incr...
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Abstract BackgroundBullous pemphigoid (BP) is associated with significant disability and comorbid health disorders that may lead to or result from hospitalization. However, little is known about the inpatient burden and comorbidities of BP. MethodsWe analyzed data from the 2002–2012 National Inpatient Sample, including a representative 20% sample of all hospitalizations in the US (n=72,108,077 adults). ResultsThe prevalences of hospitalization for BP increased from 25.84 to 32.60 cases per million inpatients from 2002 to 2012. In multivariate logistic regression models with stepwise selection, increasing age, non‐w...
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
The post Sex after the menopause appeared first on Hysterectomy Association. The menopause is a part of a woman’s life. Although most women don’t have to face this transitional period until their 40’s and 50’s, women who have a hysterectomy can expect to experience early menopause, with symptoms more severe than normal. During this time your ovaries will shut down, and you will no longer be able to conceive. Whether you are experiencing the menopause naturally or as a result of having a hysterectomy, one thing is for sure – this doesn’t have to mean the end of your sex life. Although som...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Hysterectomy Support Groups sex sexual health sexuality Source Type: news
This article reviews the evaluation, surveillance and management of patients with spinal cord injury, multiple sclerosis, spina bifida and Parkinson's disease. Recent findings: Recent studies of patients with neurogenic bladder have highlighted their risk for potentially preventable urologic complications ranging from renal failure to urinary tract infections. However, these same studies bring attention to the lack of compliance and consensus regarding the recommended evaluation of these high-risk patients. Summary: Patients with neurovesical dysfunction must be followed at regular intervals to preserve upper tract funct...
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: EVIDENCE-BASED UROLOGY: RELATION TO FEMALE UROLOGY: Edited by Roger R. Dmochowski Source Type: research
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