High PD-L1 expression indicates poor prognosis of HIV-infected patients with non-small cell lung cancer

ConclusionHigh PD-L1 expression in tumor tissue was associated with poor prognosis in HIV-infected NSCLC patients but not in non-HIV-infected NSCLC patients. These results suggest that antitumor immunity by PD-1/PD-L1 axis might be suppressed more in HIV-infected NSCLC patients as compared to their non-HIV-infected counterparts.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research