Interleukin ‐4 induces a CD44high/CD49bhigh PC3 subpopulation with tumor‐initiating characteristics

In conclusion, IL‐4 increases a PC3 subpopulation with tumor‐initiating characteristics. Thus, IL‐4, similar to other cytokines may be a regulator of tumor‐initiation and hence, may present a suitable therapy target in combination with current treatment options. This article is protected by copyright. All rights reserved

Source: Journal of Cellular Biochemistry - December 13, 2017 Category: Biochemistry Authors: Holger H. H. Erb, Fabian Guggenberger, Fr édéric R. Santer, Zoran Culig Tags: Article Source Type: research