Can bariatric surgery delay the need for knee replacement in morbidly obese osteoarthritis patients

Conclusion: Bariatric surgery when combined with dietary and exercise changes gave significant results in terms of weight loss, knee pain and function. It is an approach that tackles both obesity and OA. It is a major step forward in stemming the global epidemic of these two interlinked conditions.
Source: Journal of Minimal Access Surgery - Category: Surgery Authors: Source Type: research

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Publication date: December 2019Source: Food Research International, Volume 126Author(s): Dele Raheem, António Raposo, Oluwatoyin Bolanle Oluwole, Maaike Nieuwland, Ariana Saraiva, Conrado CarrascosaAbstractGlobally, there is a need to seek alternative sources of protein in addition to meat. This has led to considerable interest in edible insects. Such insects form part of cultures and diets in many Asian and African countries, and are an excellent source of essential nutrients, minerals, vitamins and proteins. Furthermore, they have been reported to be sustainable. The ecological importance of insects is related to ...
Source: Food Research International - Category: Food Science Source Type: research
In this study, we assessed effects of LPZ on adipocyte differentiation and function by using 3T3-L1 preadipocytes and HFD-induced obesity mice as an in vitro and in vivo model, respectively.Main methodsOil red O staining and intracellular triacylglycerol content were used to determine lipid accumulation. Glucose uptake was performed to measure mature adipocyte function. Expression of adipocyte genes was determined by qRT-PCR and immunoblotting.Key findingsLPZ has dual effects on differentiation of 3T3-L1 cells. At low concentrations, LPZ enhanced adipocyte differentiation via induction of PPARγ and C/EBPα, two ...
Source: Life Sciences - Category: Biology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
ConclusionData obtained demonstrated that solubility of Zn, Se and Mn was influenced by the mineral chemical form supplemented to the diet and by the gastrointestinal environment. The solubility of Zn, Se and Mn was not comparable with the apparent availability of Zn, Se and Mn. Nevertheless, the effect of the chemical form of the minerals was similar for the solubility of Zn, Se and Mn and the apparent availability of Zn, Se and Mn. Considering the overall results of this study, the in vitro method could replace some of the in vivo studies for a qualitative evaluation but not for a quantitative evaluation.
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
CONCLUSIONS The subgroups with increased risk of developing multiple unhealthy behaviors and the most prevalent behaviors were identified. These findings are expected to contribute to the better targeting of health promotion and preventive care. It is worth noting that, for the adoption of healthy lifestyle habits, macro-social and inter-sectoral policies are more effective.RESUMO OBJETIVO Estimar a coocorr ência dos principais fatores de risco para doenças crônicas não transmissíveis em adultos (18 a 59 anos) e idosos ( ≥ 60 anos) residentes nas capitais dos estados brasileiros e Distri...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
CONCLUSIONS This study contributed to the knowledge on the profile of confirmed cases of high severity yellow fever. The main factors associated with death were changes in renal excretion and elevated serum transaminases, especially ALT. High lethality emphasizes the need for early diagnosis and treatment, and the importance of increasing vaccination coverage.RESUMO OBJETIVO Descrever o perfil cl ínico-epidemiológico dos casos confirmados de febre amarela internados em hospital geral de referência para doenças infecciosas no estado do Rio de Janeiro, Brasil, de 11 de março de 2017 a 15 de ...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
CONCLUSIONS The necessary changes represent a major regulatory and production challenge due to the wide range of dietary supplements and markets, an effort that aims to protect the consumers ’ health. Some previous gaps in the regulatory framework were not fully solved.RESUMO OBJETIVO O novo marco regulat ório para os suplementos alimentares no Brasil instigou a presente análise do panorama atual desses produtos e os desafios impostos pelas novas diretrizes. MÉTODOS Foi realizado um estudo qualitativo, observacional e descritivo dos suplementos alimentares comercializados em lojas virtuais brasil...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
Four state attorney generals said Monday they have reached what they are calling the framework for a $48 billion agreement with three wholesale pharmaceutical distributors and two pharmaceutical companies to settle litigation tied to the country's opioid abuse epidemic. The tentative agreement, according to Pennsylvania Attorney General Josh Shapiro, was reached with Cardinal Health, McKesson, AmerisourceBergen, Johnson&Johnson, and Teva Pharmaceuticals Ltd. AmerisourceBergen (NYSE: ABC) is…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Locations - National Spine &Pain Centers treatingpain.com Hey all, anyone familiar with the National Spine and Pain practices operating out of the maryland and northern virginia area? A good practice to work for? Any idea what the compensation is for the pain docs working there?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Innate immunity is critical in the early containment of influenza A virus (IAV) infection and surfactant protein D (SP-D) plays a crucial role in innate defense against IAV in the lungs. Multivalent lectin-mediated interactions of SP-D with IAVs result in viral aggregation, reduced epithelial infection, and enhanced IAV clearance by phagocytic cells. Previous studies showed that porcine SP-D (pSP-D) exhibits distinct antiviral activity against IAV as compared to human SP-D (hSP-D), mainly due to key residues in the lectin domain of pSP-D that contribute to its profound neutralizing activity. These observations provided the...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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