A novel pathway activated by somatostatin receptor type 2 (SST2): Inhibition of pituitary tumor cell migration and invasion through cytoskeleton protein recruitment

In conclusion, we demonstrated that SST2 inhibits rat and human tumoral somatotrophs migration and invasion through a molecular mechanism that involves FLNA‐dependent cofilin recruitment and phosphorylation. This article is protected by copyright. All rights reserved.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fijc.31205

Source: International Journal of Cancer - December 11, 2017 Category: Cancer & Oncology Authors: E Peverelli, E Giardino, D Treppiedi, R Catalano, F Mangili, M Locatelli, AG Lania, M Arosio, A Spada, G Mantovani Tags: Research Article Source Type: research

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