Long ‐term cardiovascular re‐programming by short‐term perinatal exposure to nicotine's main metabolite cotinine

ConclusionCotinine has subtle, enduring developmental consequences. Some cardiovascular effects of nicotine can plausibly arise via conversion to cotinine. Low‐level exposure to this metabolite may pose unrecognized perinatal risks. Adults must avoid inadvertently exposing a fetus or infant to cotinine as well as nicotine.This article is protected by copyright. All rights reserved.

Source: Acta Paediatrica - December 9, 2017 Category: Pediatrics Authors: Stefano Bastianini, Viviana Lo Martire, Alessandro Silvani, Giovanna Zoccoli, Chiara Berteotti, Hugo Lagercrantz, Anders Arner, Gary Cohen Tags: Regular Article Source Type: research