Impact of analgesics on executive function and memory in the Alzheimer's Disease Neuroimaging Initiative Database

Conclusions NSAID use was associated with higher executive function, and memory scores in certain subjects and larger cortical volumes in particular regions. Limitations of the study include secondary analysis of existing data and the possibility of confounding. Implications These results suggest it is important to consider the secondary effects of medications when choosing a treatment regimen. Further prospective studies are needed to examine the role of analgesics on cognition and whether NSAIDs act through cortical dimension changes and how they are related to gender and cognitive diagnosis.
Source: Scandinavian Journal of Pain - Category: Anesthesiology Source Type: research