Assessment of Ocriplasmin Effects on the Vitreoretinal Compartment in Porcine and Human Model Systems.

In conclusion, transient hyperreflective spots and fluid in a porcine ocriplasmin-induced PVD model did not correlate with retinal ECM rearrangement nor inflammation. Reversible in vitro effects on blood-retinal barrier permeability provide grounds for a hypothesis on the mechanisms behind transient subretinal fluid observed in ocriplasmin-treated patients. PMID: 29214073 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/29214073?dopt=Abstract

Source: Journal of Ophthalmology - December 9, 2017 Category: Opthalmology Tags: J Ophthalmol Source Type: research

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