Fragmentation level determines mitochondrial damage response and subsequently the fate of cancer cells exposed to carbon ions.

CONCLUSION: We proposed a stress response model to provide a mechanistic explanation for the mitochondrial damage response to high-LET carbon ions.
PMID: 29208514 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 2, 2017 Category: Radiology Authors: Jin X, Zheng X, Li F, Liu B, Li H, Hirayama R, Li P, Liu X, Shen G, Li Q Tags: Radiother Oncol Source Type: research