Neovascular Prostate-Specific Membrane Antigen Expression Is Associated with Improved Overall Survival under Palliative Chemotherapy in Patients with Pancreatic Ductal Adenocarcinoma.

Conclusion: PSMA expression in tumor-associated neovasculature is a common feature and associated with improved overall survival under palliative chemotherapy in PDAC. Our results point towards a possible association between PSMA expression and response to therapy which might be based on enhanced intratumoral bioavailability of systemic chemotherapy.
PMID: 29209626 [PubMed - in process]

Source: Biomed Res - December 8, 2017 Category: Research Authors: Stock K, Steinestel K, Wiesch R, Mikesch JH, Hansmeier A, Trautmann M, Beller N, Rehkämper J, Wardelmann E, Heitkötter B, Hartmann W, Sperveslage J, Huss S Tags: Biomed Res Int Source Type: research