Maybe the healthiest wine in the world

When I was in South Africa last year, I met a revolutionary winemaker… His wine was completely organic. It had no toxins, and it contained powerful antioxidant properties. It was infused with a local herb called rooibos, also known as “red bush.” You may have seen rooibos tea on supermarket shelves. I immediately knew this wine should be made widely available in America — and I’m still hopeful a distributor will bring it here. I enjoy a nice glass of red wine from time to time, but the trouble with most of the wines sold in America is that they’re loaded with dangerous chemicals. Winemaking was once a very simple process. You would pick wild grapes, mash them and leave them to ferment for a while. You wouldn’t add anything. The result was a low-alcohol beverage rich in antioxidants with real health benefits. Even your primal ancestors used fermented fruit juice — for medicine as well as for enjoyment. But the wine in your glass today is much different from your ancestor’s traditional brew. Modern producers now doctor their wines to get a standard, predictable beverage that can be produced and sold at low cost. But there is a big problem: Almost 80 chemical additives have been approved in the U.S. for making wine — yet only 38 of these substances have been determined to be safe. Common wine additives include: Sulfur dioxide. Low levels of sulfites occur naturally in fermented grape juice. But winemakers often add su...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Health additives natural organic Sulfites wine Source Type: news

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ConclusionIn conclusion, hypothalamic Pomc as well as Mc4r, both of which are reduced in type 1 diabetic mice, are required for normal counterregulatory responses to hypoglycemia. Therefore, enhancing MC4R function may improve hypoglycemia counterregulation in diabetes.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
CONCLUSION: This is the first published report of diffuse alveolar bleeding in a patient with multiple sclerosis treated with alemtuzumab. Four similar cases in patients treated for multiple sclerosis and several fatal cases in patients treated for other conditions are registered at the World Health Organization database of suspected adverse events (VIgiBase©), underscoring that this is a serious and possibly under-recognized complication of alemtuzumab which can also occur in the treatment of multiple sclerosis. The clinician should consider the possibility of diffuse pulmonary haemorrhage in patients with sudden ons...
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research
Antonella Stoppacciaro, Serena Di Vito, Patrizia Filetici
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 20 November 2018Source: Pharmacology &TherapeuticsAuthor(s): Patrycja Kleczkowska, Katarzyna Nowicka, Magdalena Bujalska-Zadrozny, Emmanuel HermansAbstractHybrid compounds (also known as chimeras, designed multiple ligands, bivalent compounds) are chemical units where two active components, usually possessing affinity and selectivity for distinct molecular targets, are combined as a single chemical entity. The rationale for using a chimeric approach is well documented as such novel drugs are characterized by their enhanced enzymatic stability and biological activity. This allows their...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Publication date: 5 February 2019Source: Journal of Pharmaceutical and Biomedical Analysis, Volume 164Author(s): Jong-Woo Jeong, Ji-Hoon Oh, Yu-Geun Ji, Yu-Mi Shin, Myeong Hwi Lee, Nam Sook Kang, Weontae Lee, Sung-Sub Kim, Tae-Yoon Kim, Tae-Sung KooAbstractThe antioxidant enzyme human extracellular superoxide dismutase (SOD3) is a promising biopharmaceutical candidate for the treatment of various diseases. To support the early development of SOD3 as a biopharmaceutical, a simple, sensitive, and rapid liquid chromatography tandem mass spectrometry procedure was developed and validated for the determination of SOD3 levels in...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
In conclusion, C. chrysanthus flowers can be suggested as a source of bioactive components with potential use against chronic disorders caused by oxidative stress. Future in-depth studies are recommended to determine the biological effects of isolated compounds from C. chrysanthus to identify the main compounds modulating the observed activities.
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
In this study, a PEG-modified liposome was developed for efficiently encapsulating CBZ, thus enhancing its specific tumor inhibition effect and reducing the systemic toxicity. It was found that the loading efficiency of CBZ into the liposome could be improved with the increase of lipophilic materials, as it could be over 80% under the weight ratio of 20:1 (total lipid: CBZ). The diameter of CBZ loaded liposome (CBZ@Lipo) was ∼100 nm. And the liposome suspending in aqueous medium was stable at 4 °C for at least one month, according to the change of its size distribution. The killing ability of CBZ@Lipo to cancer cel...
Source: Asian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research
ConclusionClassical pharmaceutical procedures of Mahalaxmi Vilas Rasa showed converting the macro elements into therapeutically effective medicines of micro form. Standards laid down in this study certainly utilized as an important tool for standardization and quality assurance of this herbo-mineral formulation.
Source: Journal of Ayurveda and Integrative Medicine - Category: Complementary Medicine Source Type: research
This study was aimed at investigating the inhibitory potential of A. senegalensis leaf extracts and fractions on the activities of some enzymes (α-amylase and α-glucosidase) linked to diabetes. Plant samples were extracted with n-hexane (HEX), ethyl cetate (EtOAc) and ethanol (EtOH) and the extracts were subjected to in vitro antidiabetic studies. The most active extract was further fractionated using column chromatography and the fractions obtained were screened for the inhibitory activities whilst the possible bioactive compounds were determined by Gas Chromatography Mass Spectroscopy (GC-MS). From the result...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
Publication date: Available online 20 November 2018Source: Journal of Herbal MedicineAuthor(s): Atefeh Zare, Zeinab Moshfeghy, Mohammad M. Zarshenas, Bahia Namavar jahromi, Marzieh Akbarzadeh, Mehrab SayadiAbstractThe current study aimed to compare the effects of Quercus brantii Lindl. vaginal cream in combination with metronidazole tablet on Bacterial Vaginosis (BV). A total of 176 eligible women with BV were enrolled. Diagnosis was based on having 3 or more signs described by Amsel’s criteria and a Nugent score of ≥7. Symptoms were evaluated before and after treatments. Participants were divided into two experim...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
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