Discordance between mass spectrometry and immunometric IGF-1 assay in pituitary disease: a prospective study

ConclusionsIGF-1 results may differ after switching from an older immunoassay to a consensus-compliant assay such as LC-MS. Clinicians should consider the potential impact of assay switching before altering treatment due to discrepant results, particularly in patients monitored over time, such as those with acromegaly and GH deficiency.
Source: Pituitary - Category: Endocrinology Source Type: research