Birth control pills slightly raise risk of breast cancer, study suggests

About 140 million women use some type of hormonal contraception, including about 16 million in the United States
Source: Health News: - Category: Consumer Health News Source Type: news

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Sara M. Tolaney, MD, MPH shares the MONARCH 2 study in pre and peri-menopausal ER+, HER2- breast cancer patients at ASCO 2018. Author: obr Added: 07/18/2018
Source: Oncology Tube - Category: Cancer & Oncology Source Type: podcasts
Conclusions: MiR-4319 suppresses the malignancy of TNBC by regulating self-renewal and tumorigenesis of stem cells and might be a remarkable prognostic factor or therapeutic target for patients with TNBC.Cell Physiol Biochem 2018;48:593 –604
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Conclusions: HIF-2 α expression may be associated with the carcinogenesis of CRC, which is higher in males than in females, negatively linked to tumor differentiation, and correlated with a worse DFS of CRC. Additional prospective studies are needed.Cell Physiol Biochem 2018;48:516 –527
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Publication date: Available online 16 October 2017Source: Clinica Chimica ActaAuthor(s): Wei-Bing Yin, Ming-Guang Yan, Xiao Fang, Jian-Jun Guo, Wei Xiong, Ruo-Peng ZhangAbstractBackgroundCircular RNAs (circRNAs) are a class of non-coding RNAs (ncRNAs) and characterized by covalently closed loop without 5′ and 3′ end. Recently, the diagnostic value of circRNAs has received more and more attention. However, the in-depth study about circRNAs diagnosis in breast cancer is still rarely reported. In present study, we try to investigate the circRNAs expression profiles in breast cancer peripheral blood and discover va...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
CONCLUSIONS: Pilates should be considered for patients with NCDs, as it improves exercise tolerance. Future studies with robust methodologies are still needed to clarify its effectiveness on outcomes with moderate, limited or conflicting evidence and to establish the most suitable intervention protocol. PMID: 30012382 [PubMed - in process]
Source: Complementary Therapies in Medicine - Category: Complementary Medicine Authors: Tags: Complement Ther Med Source Type: research
(MedPage Today) -- New indications for ribociclib sped through under'real-time'review program
Source: MedPage Today Public Health - Category: American Health Source Type: news
(CNN) — People who eat dinner before 9 p.m. — or at least two hours before going to sleep — have a 20% lower risk of breast and prostate cancer than those who eat after 10 p.m. or go to bed shortly after supper, researchers found. “The mechanisms are not clear,” said Dr. Manolis Kogevinas, a research professor at the Barcelona Institute for Global Health in Spain and lead author of a new study on the topic. “What we know from experimental studies is that we are conditioned to function in different parts of the day. We — not only humans but all living organisms — have develope...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Cancer Local TV Source Type: news
The agency has used two new programs that allow real-time review of clinical data to approve extensions to the use of ribociclib in breast cancer.FDA Approvals
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news
Authors: Kim C, Go EJ, Kim A Abstract PURPOSE: To identify miRNAs associated with distant recurrence during tamoxifen treatment and build a recurrence prediction model. MATERIALS AND METHODS: We measured the expression of five miRNAs (miR-134, miR-125b-5P, miRNA-30a, miR-10a-5p, and miR-222). A total of 176 tumor tissues from 176 patients who had hormone receptor positive breast cancer with tamoxifen treatment were used to measure miRNA expression using quantitative real-time PCR (qRT-PCR). RESULTS: The five miRNAs were all up-regulated in distant recurrence cases within 5 years after surgery and during tam...
Source: Biomarkers - Category: Research Tags: Biomarkers Source Type: research
Caveolin‑1 enhances RANKL‑induced gastric cancer cell migration. Oncol Rep. 2018 Jul 05;: Authors: Wang Y, Song Y, Che X, Zhang L, Wang Q, Zhang X, Qu J, Li Z, Xu L, Zhang Y, Fan Y, Hou K, Liu Y, Qu X Abstract The classical pathway involving receptor activator of nuclear factor‑κB (RANK) and its ligand (RANKL) induces the activation of osteoclasts and the migration of a variety of tumor cells, including breast and lung cancer. In our previous study, the expression of RANK was identified on the surface of gastric cancer cells, however, whether the RANKL/RANK pathway is involved in the regula...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
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