Hormonal birth control linked to increased breast cancer risk, study says
The study included 1.8 million women over the course of nearly 11 years.
Germline BRCA mutations and other HR genes may offer biomarkers for response to this treatment.
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Fay Nicolson, Lauren E. Jamieson, Samuel Mabbott, Konstantinos Plakas, Neil C. Shand, Michael R. Detty, Duncan Graham, Karen Faulds Multiplexed imaging of three nanotags within live breast cancer tumour models through depths of 10 mm using handheld SESORRS. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Condition: Breast Cancer Intervention: Drug: T-DM1 Sponsors: Dana-Farber Cancer Institute; Susan G. Komen Breast Cancer Foundation; Gateway for Cancer Research Not yet recruiting
We describe 2 patients with local recurrence 3 and 9 years, respectively, after mastectomy with DIEAP (deep inferior epigastric artery perforator) flap breast reconstruction. Patients generally present with a palpable mass, pain, or other visible abnormalities. Various imaging techniques are helpful, always completed by biopsy to characterize the tumour. A repeated sentinel node procedure can be useful in staging. The treatment of the local recurrence needs to be determined in a multidisciplinary team consultation.Case Rep Oncol 2018;11:493 –498
Lauren Trintinaglia, Lucas Poitevin Bandinelli, Rodrigo Grassi-Oliveira, Laura Esteves Petersen, Marcelo Anzolin, Bruna Luz Correa, Jaqueline Bohrer Schuch, Mois és Evandro Bauer
BREAST cancer symptoms and signs develop when a few cells in this area start to divide uncontrollably. The most common cancer in women, there are also rare cases of the cancer developing in men. Watch out for these warning signs of breast cancer.
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.8b00392
ACS Applied Materials&InterfacesDOI: 10.1021/acsami.8b03822
Cancers, Vol. 10, Pages 234: Morphomechanical Alterations Induced by Transforming Growth Factor-β1 in Epithelial Breast Cancer Cells Cancers doi: 10.3390/cancers10070234 Authors: Mariafrancesca Cascione Valeria De Matteis Chiara C. Toma Stefano Leporatti The Epithelial to mesenchymal transition (EMT) is the process that drives epithelial tumor cells to acquire an invasive phenotype. The role of transforming growth factor-β1 (TGF-β1) in EMT is still debated. We used confocal laser scanning microscopy and scanning force spectroscopy to perform a morphomechanical analysis on epithelial bre...