Urinary metabolomics-based molecular sub-phenotyping of the U-BIOPRED asthma cohort

Conclusions: SA evidence an altered urinary metabolic profile relative to HC. These shifts are associated with tryptophan metabolism, which may represent a useful strategy for sub-phenotyping asthma.

Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Wheelock, C., Naz, S., Reinke, S., Chaleckis, R., Schofield, J., Skipp, P., Bigler, J., Loza, M., Baribaud, F., Bakke, P., Caruso, M., Chanez, P., Fowler, S., Horvath, K., Krug, N., Montuschi, P., Sanak, M., Sandstrom, T., Shaw, D., Chung, F., Djukanovic, Tags: Molecular Pathology and Functional Genomics Source Type: research