Modulation of pro-inflammatory and anti-viral responses in BEAS2B cells by glucocorticoid agonists

In conclusion, we showed the expected inhibitory effect of FP on pro-inflammatory cytokines and in addition a suppression of the cellular anti-viral response and an enhanced viral replication. These studies may have implications for the use of ICS during virally induced exacerbations.

Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Marcellini, A., Swieboda, D., Guedan, A., Papi, A., Johnston, S. L., Solari, R. Tags: Airway Pharmacology and Treatment Source Type: research