Mood, quality of life and functional exercise capacity in patients with lung cancer and comorbid hypertension

Conclusion: Patients with lung cancer and comorbid hypertension had poorer functional exercise capacity than those without hypertension, despite similar symptoms of anxiety and depression, and quality of life. Hypertension in these patients seems to affect physical performance outcomes more than psychological outcomes.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Physiotherapists Source Type: research

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Abstract Natural medicinal substances (NMS) have great inconsistency due to chemical variability, seriously limiting their development as therapeutics. Here, we chose toad venom with anti-tumor activities as a model and developed a pipeline of metabolomics-based screening and quality consistency control (MSQCC) as one potential solution to this long-standing problem. Our study firstly exemplified the power of the co-correlation screen of metabolomic and biological profiles of 180 fractions prepared from natural heterogeneous venom samples, to identify a series of bufadinolides as quality control markers for cancer...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Paeoniflorin inhibits IL-1β-induced MMP secretion via the NF-κB pathway in chondrocytes. Exp Ther Med. 2018 Aug;16(2):1513-1519 Authors: Hu PF, Sun FF, Jiang LF, Bao JP, Wu LD Abstract Paeoniflorin serves important cellular roles, exerting anti-cancer, anti-inflammatory and anti-pulmonary fibrosis effects and possesses immune-modulatory properties. However, the exact role of paeoniflorin in the pathogenesis of osteoarthritis (OA) remains unclear. The aim of the present study was to investigate the effects of paeoniflorin on articular surfaces in vitro. Rat chondrocytes were cultured in vitro...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Zhang M, Liu J, Li M, Zhang S, Lu Y, Liang Y, Zhao K, Li Y Abstract Glioblastoma multiforme (GBM) is a malignant tumor caused by complex pathological mechanisms, and is characterized by a high rate of cancer-related mortality and poor patient prognosis. Overgrowth of cancer cells, which results from the inhibition of cell apoptosis and/or the promotion of cell proliferation, leads to the progression of GBM. Therefore, studies into the regulatory mechanisms of cancer cell growth in GBM are required to identify potential therapeutic targets and improve treatment for GBM. In the present study, the role of ins...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
The recent suicides of highly regarded fashion designer Kate Spade and television celebrity chef and author Anthony Bourdain remind us this mental health crisis can touch anyone. Cancer patients are no exception. According to the Centers for Disease Control and Prevention (CDC), suicide rates between 1999 and 2016 have risen more than 30 percent in half of the country and by nearly 60 percent in some states. This trend is particularly worrisome for cancer patients because this group has a higher suicide risk than the general public. For mesothelioma patients and the people who care for them, one part of this picture deser...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
This study examined provider communications regarding cigarette and non-cigarette tobacco products among adults with chronic conditions.DesignCross-sectional study drawn from two waves (2013 –2014) of the National Survey on Drug Use and Health (NSDUH).ParticipantsAdults ( ≥ 18 years) who used tobacco in the past year.Main MeasuresPrevalence of tobacco use included past-year use of cigarettes, cigars, or smokeless tobacco among those with and without chronic conditions. Chronic conditions included asthma, anxiety, coronary heart disease, depression, diabetes, hepatitis, HIV, hypertension, lung cancer, stroke, ...
Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
Conclusion: Comorbid disease was frequently recorded in this asthma population. All-cause mortality for the study population did not differ from the Swedish population overall, but a higher death rate due to pulmonary causes (mainly COPD) was seen among the asthma patients.Sponsor: AstraZeneca.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 1.6 General Practice and Primary Care Source Type: research
Conclusions: The prevalence of comorbidities in patients with stable COPD was high. Mortality in these patients is related to the number of comorbidities and anxiolytic treatment. Mortality was higher in patients with 2 o more comorbidities.Funded by NEUMOSUR.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 5.2 Monitoring Airway Disease Source Type: research
Publication date: Available online 3 September 2016 Source:The Lancet Respiratory Medicine Author(s): Christopher S King, Steven D Nathan Despite the development of pharmacological therapies that are effective in slowing the progression of idiopathic pulmonary fibrosis (IPF), it remains a debilitating and lethal condition. In addition to the adverse effects caused by pulmonary fibrosis, most patients with IPF have associated comorbid conditions, which might negatively affect functional status, quality of life, and survival. Comorbid conditions can be pulmonary or extrapulmonary. Pulmonary comorbidities include pulmonary h...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Kendra and Jay Jeffcoat are the quintessential baby boomer couple. Kendra, 69, recently retired after a long and successful career as a college professor and administrator. Jay, 70, who spent his college years as student body president at the University of California, Santa Barbara, protesting the Vietnam War, continues to work full time as a corporate attorney in San Diego. In January 2013, Kendra was diagnosed with stage 4 lung cancer, which had metastasized in her brain. She never smoked, nor was she around secondhand smoke. But as Healthline noted in November 2014, lung cancer among women who don't smoke is on the ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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