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Comparison of dose volume parameters evaluated using three forward planning - optimization techniques in cervical cancer brachytherapy involving two applicators.

Conclusions: Fletcher applicator generates higher dose to both CTV and organs at risk (2 cc volumes) after all optimization techniques. Dose restriction to rectum is possible using graphical optimization only during selected HDR fractionation schedules. Bladder always receives dose higher than recommended, and 2 cc sigmoid colon always gets permissible dose. Contrarily, graphical optimization with ring applicators fulfills all dose volume objectives in all HDR fractionations practiced. PMID: 29204164 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

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Conclusion Smoking, infectious agents, and betel nut chewing appear to be important contributors to the burden of cancer in Guam. Earlier onset of cancer in Guam suggests earlier age of exposure to key risk factors and/or a more aggressive pathogenesis. Contrasting cancer patterns within Guam and between Guam and Hawaii underscore the potential influence of genes, lifestyle, and environmental factors on cancer development and progression.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
Author Affiliations open 1 McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada 2 Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain 3 Universitat Pompeu Fabra (UPF), Barcelona, Spain 4 CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain 5 School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada 6 Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA 7 Department of Economics, Brigham Young University, Provo, Utah, USA 8 Population Studies Division, Health Canada, Ottawa, Cana...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
CONCLUSIONS: POGS reduced treatment plan optimization time approximately 18 times for RSBT with similar HR-CTV D90, organ at risk (OAR) D2cc values, and EQD2 values compared to CPLEX, which is significant progress toward clinical translation of RSBT. This article is protected by copyright. All rights reserved. PMID: 28744870 [PubMed - as supplied by publisher]
Source: Physica Medica - Category: Physics Authors: Tags: Med Phys Source Type: research
Conclusions/interpretationDiabetes was associated with a 26% increased risk of death from any cancer in Asians. The pattern of associations with specific cancers suggests the need for better control (prevention, detection, management) of the growing epidemic of diabetes (as well as obesity), in order to reduce cancer mortality.
Source: Diabetologia - Category: Endocrinology Source Type: research
Researchers have been trying to understand why up to 85 percent of women experience recurrence of high-grade serous ovarian cancer — the most common subtype of ovarian cancer — after standard treatment with the chemotherapy drug carboplatin.Preclinical research from Dr. Sanaz Memarzadeh, who is a member of the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, has potentially solved this mystery and pinpointed a combination therapy that may be effective for up to 50 percent of women with ovarian cancer.Memarzadeh ’s research, published in the journal Preci...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Six hundred ninety-seven histologically confirmed cases of cancer were seen in the three-year period, 1987 to 1989, at Asir Central Hospital in Abha, Saudi Arabia. Percentage (crude relative) frequencies of cancer at various sites were determined. The most common cancer sites among males were skin, liver, lymphoid tissue (i.e., non-Hodgkin's lymphomas), bladder, blood (leukemias), stomach, colon, esophagus, central nervous system, and prostate. Skin cancer was also the most common cancer among females, followed by the breast, lymphoid tissue (non-Hodgkin's lymphomas), blood (leukemias), thyroid, stomach, colon, oral cavity...
Source: Annals of Saudi Medicine - Category: Journals (General) Tags: ISSUE 3 Source Type: research
Conditions:   Radiation Therapy;   Cancer;   Cancer of Anus;   Cancer of Bladder;   Cancer of Cervix;   Cancer of Colon;   Cancer of Rectum;   Cancer of Esophagus;   Cancer of Gallbladder;   Cancer of Liver;   Cancer of Ovary;   Cancer of Pancreas;   Cancer of Prostate;   C ancer of Kidney and Renal Pelvis;   Cancer of Stomach;   Cancer of Testis;   Cancer of Uterus;  ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Main points include: Survival at 1 year and 5 years after diagnosis improved for the 8 cancers examined in this report (colon, breast, cervix,prostate, oesophagus, stomach, bladder, lung) among adults diagnosed in England between 2003 and 2010. Differences in net survival between the 4 NHS Regions are generally small, of the order 1% to 3%. Survival improved slightly but consistently in all 4 regions for 7 of the 8 cancers.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Conclusion Our study showed increased incidence in most cancers and provided baseline estimates of stage-specific RSRs among the Taiwanese adult population. Continuous surveillance may help politicians to improve health policies and cancer care in Taiwan.
Source: Journal of the Formosan Medical Association - Category: Journals (General) Source Type: research
CONCLUSIONS: Hydrogel instillation is a useful tool for recto-vaginal separation during cervical cancer brachytherapy. It increases therapeutic ratio without any adverse event. PMID: 27895681 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
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