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Presentation and outcome of frequent and rare sarcoma histologic subtypes: A study of 10,262 patients with localized visceral/soft tissue sarcoma managed in reference centers

The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. METHODSThe authors conducted a retrospective multicenter study of 12,262 patients who were treated between January 1980 and 31 December 2013 in French Sarcoma Group centers and enrolled in the “Conticabase.” Diagnoses were systematically reviewed by expert pathologists, and entities were classified according to the 2013 World Health Organization classification. Diagnostic characteristics, treatments, and outcomes are described for the entire cohort, for the subgroup of patients with translocation‐related sarcomas, and for 9 different histologic subtypes. RESULTSThe results stressed the magnitude of heterogeneity among adult sarcomas. For example, compared with other sarcomas, translocation‐related sarcomas (2143 tumors; 20.8%) were associated with a younger age at presentation (40.6 vs 60.0 years; P 
Source: Cancer - Category: Cancer & Oncology Authors: Tags: Original Article Source Type: research

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