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Extreme Low-Cal Diet Led to Diabetes Remission

An extremely low-calorie diet put type 2 diabetes into remission for many patients, according to a new study.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Authors: Huang H, Shetty S, Bauer E, Lang K Abstract OBJECTIVE: To estimate the proportion of patients with moderate to severe chronic kidney disease (CKD) whose initial DPP4-i dosage was concordant with prescribing information (label) recommendations in the United States. METHODS: Adult patients with T2DM who initiated a DPP4-i (linagliptin, sitagliptin, saxagliptin) between Jan 1, 2011 and Jun 30, 2014 were identified using electronic medical records and administrative claims, with index date being the date of first observed DPP4-i treatment. Patients were required to have CKD Stage 3b, 4 or 5 (eGFR value
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Conclusions: In diabetic patients with NAFLD, light or moderate lifetime alcohol consumption was not significantly associated with liver fibrosis. The impact of lifetime alcohol intake on fibrosis progression and diabetic comorbidities, in particular obstructive sleep apnea and hypertriglyceridemia, requires further investigation. PMID: 29226116 [PubMed - in process]
Source: Canadian Journal of Gastroenterology - Category: Gastroenterology Tags: Can J Gastroenterol Hepatol Source Type: research
Conditions:   Type2 Diabetes;   Depression Interventions:   Behavioral: Program ACTIVE Exercise;   Behavioral: Program ACTIVE CBT;   Behavioral: Program ACTIVE;   Behavioral: Usual Care - No intervention Sponsors:   Indiana University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   West Virginia University;   Ohio University;   University of Michigan Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   NAFLD;   Diabetes Mellitus, Type 2;   Hypertriglyceridemia;   Fatty Liver, Nonalcoholic Interventions:   Drug: ISIS 703802;   Drug: Placebo Sponsors:   Ionis Pharmaceuticals, Inc.;   Akcea Therapeutics Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: CREDENCE will provide definitive evidence about the effects of canagliflozin on renal (and cardiovascular) outcomes in patients with type 2 diabetes and established kidney disease.Trial Registration: EudraCT number: 2013-004494-28; ClinicalTrials.gov identifier: NCT02065791.
Source: American Journal of Nephrology - Category: Neurology Source Type: research
This study enrolled 7,804 male workers free of diabetes in 1986. CRF was measured using a cycle ergometer, and maximal oxygen uptake was estimated. During 1986-2009, participants were followed for development of type 2 diabetes, which was diagnosed using fasting blood tests, self-administered questionnaires, or oral glucose tolerance tests after urinary tests from annual health checkups. Hazard ratios for the incidence of type 2 diabetes were estimated using Cox proportional hazards models. RESULTS: During the follow-up period, 1,047 men developed type 2 diabetes. In analyses by follow-up periods (1986-1993, 1994-2001,...
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
Authors: Bazargan-Hejazi S, Arroyo JS, Hsia S, Brojeni NR, Pan D Abstract Objective: To investigate: 1) the racial/ethnic disparities in meeting the recommended physical activity as measured by subjective vs objective measures in a national sample of individuals with type 2 diabetes mellitus; and 2) the racial/ethnic differences with respect to the magnitude of the discrepancy between self-reported and objectively measured moderate-to-vigorous intensity aerobic physical activity (MVPA). Methods: We used data from the National Health and Nutrition Examination Survey (NHANES) 2003-06 to calculate and compare the ...
Source: Ethnicity and Disease - Category: International Medicine & Public Health Tags: Ethn Dis Source Type: research
(Natural News) A comprehensive study reveals evidence of the beneficial properties of substituting whole grains to refined grain diets – such as losing weight and reducing inflammation – particularly among overweight people who are most at risk of developing cardiovascular diseases and type-2 diabetes. Researchers from the National Food Institute worked together with the Department...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
We report on the individual histological features and scoring systems of NAFLD: the NAFLD activity score (NAS) introduced by the NASH-Clinical Research Network, the "Fatty Liver Inhibition of Progression" algorithm and Steatosis, Activity, and Fibrosis (SAF) score. Pros and cons of histological classifications in NASH are discussed. Special emphasis is given to liver histopathology in some high-risk patient groups, such as those with severe obesity and type 2 diabetes. Moreover, we also examine the relationship between liver histopathology and clinical features, and the impact of liver histopathology on the long-...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
In this volume of The Journal, Gidding et  al, representing the TODAY study, report longitudinal data on cardiac biomarkers and their relationship to cardiovascular disease (CVD) risk factors and left ventricular structure and function in youth with type 2 diabetes (T2D). BNP, TNF-α, and troponin were elevated and increased over the 5-yea r study. However, these markers did not necessarily persist in individuals or in relationship to glycemia or CVD structure or function. The authors conclude that elevated serum concentrations of cardiac biomarkers were common in youth with T2D, but their clinical significance i...
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: The Editors' Perspectives Source Type: research
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