Arboviruses and their related infections in China: A comprehensive field and laboratory investigation over the last 3 decades
Summary Since the 1980s, a comprehensive field and laboratory investigation has been conducted throughout China, and a total of 29 virus species belonging to 7 families and 13 genera were identified through virological, morphological, and immunological methods, as well as whole‐genome sequencing and molecular genetic analyses. Most of the virus isolates belong to 9 genera in the families Flaviviridae, Bunyaviridae, Togaviridae, and Reoviridae. Among them, 4 genera (Orthobunyavirus, Bunyavirus, Phlebovirus, and Nairovirus) belong to the family Bunyaviridae and 3 genera (Seadonavirus, Orbivirus, and Cypovirus) belong to the family Reoviridae. Analyses of the relationships between viruses and human/animal diseases indicated that Japanese encephalitis virus, dengue virus, severe fever with thrombocytopenia syndrome virus, tick‐borne encephalitis virus, Crimean‐Congo hemorrhagic fever virus, West Nile virus, and Tahyna virus can cause human and animal infections and disease epidemics in China. This review systematically introduces the current status of the diversity and geographical distribution of arboviruses and vectors in China. In addition, our results provide strong technical support for the prevention and control of arboviral diseases, the treatment of epidemics, and the early warning and prediction of diseases, and so they are significant for the control and prevention of arboviral diseases in Asia and around the world.
U.S. Senate, Committee on Health, Education, Labor, and Pensions. 11/30/2017 This two-hour, 30-minute Congressional hearing discusses the current opioid crisis, with providers, public safety officials, and state health officials who are on the front lines fighting the epidemic, speak to what is happening on the ground, and what more Congress can do to help them address the crisis. Topics include Rhode Island's Strategic Plan to Address Opioid Addiction and Overdose, which recommended specific, evidence-based strategies in four areas: prevention, rescue, treatment, and recovery. (Video or Multimedia)
Brookings Institution. 11/03/2017 These presentations and panel discussion focus on how public policy can address the opioid epidemic. Speakers discuss the underlying issues that contributed to the opioid crisis, increased rates of alcoholism and suicide among certain segments of the American population, and the report of the President's Commission on Combatting Opioid Drug Addiction and the Opioid Crisis. (Video or Multimedia)
Conclusion: Dengue virus infection results in immense morbidity and substantial mortality. PMID: 29225757 [PubMed]
The small-molecule inhibitor, named NGI-1, shows promise as a treatment for Zika, dengue, West Nile, and yellow fever viruses.
America ’s opioid and heroin crisis was declared a national public health emergency last month. Read about its devastating impact on Americas workforce.
Record hurricanes, data breaches, colliding black holes and drug epidemics—the most important science stories of the year -- Read more on ScientificAmerican.com
To the Editor: A frontal band of scarring alopecia with eyebrow involvement in postmenopausal women (ie, frontal fibrosing alopecia [FFA]) evolved from a “recently described disease” to the status of “a growing epidemic” in less than 2 decades. Since the first report by Kossard,1 additional features and variants not contemplated in the original description have been incorporated into the clinical picture. For such, I read with great interest the paper by Rossi et al reporting 3 unusual clinical patterns of FFA.
Acne vulgaris is an epidemic inflammatory disease of the human sebaceous follicle and represents the most common skin disease affecting about 85% of adolescents in Westernized populations. Acne vulgaris is primarily a disease of wealthy countries and exhibits higher prevalence rates in developed compared with developing countries. No acne has been found in non-Westernized populations still living under Paleolithic dietary conditions constraining hyperglycemic carbohydrates, milk, and dairy products.
The metabolic syndrome (MetS), also termed syndrome X, the deadly quartet, and insulin resistance syndrome, has been of interest for many years; however, there has been a striking increase in the prevalence of MetS over the last few decades, coinciding with the global epidemic of obesity and diabetes mellitus.1,2 MetS is a constellation of several clinical and laboratory findings that have been reported to be associated with numerous medical and dermatologic conditions, such as psoriasis, hidradenitis suppurativa, and acne vulgaris; moreover, the severity of psoriasis is significantly associated with MetS at higher psorias...