Deletion Involving the 7q31-32 Band at the CADPS2 Gene Locus in a Patient with Autism Spectrum Disorder and Recurrent Psychotic Syndrome Triggered by Stress.
Deletion Involving the 7q31-32 Band at the CADPS2 Gene Locus in a Patient with Autism Spectrum Disorder and Recurrent Psychotic Syndrome Triggered by Stress. Case Rep Psychiatry. 2017;2017:4254152 Authors: Grabowski PAP, Bello AF, Rodrigues DL, Forbeci MJ, Motter V, Raskin S Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disorder marked by impairments in social functioning, language, communication, and behavior. Recent genome-wide association studies show some microdeletions on the 7q31-32 region, including the CADPS2 locus in autistic patients. This paper reports the case of a patient with ASD and recurrent psychotic syndrome, in which a deletion on the 7q31-32 band at the CADPS2 gene locus was evidenced, as well as a brief review of the literature on the CADPS2 gene and its association with ASD. PMID: 29201482 [PubMed]
LONDON MARATHON runners today have thousands of different reasons for putting their body through hell. Here one of them, a father, recalls the moment he learned his son has autism and explains why he's taking on the challenge...
A recent study looks at the links between the immune system, gut bacteria, and autism spectrum disorders. It uncovers some interesting interactions.
Hans Asperger, the Austrian pediatrician who pioneered research into autism and after whom Asperger syndrome is named,"actively cooperated" with a Nazi program under which disabled children were killed, an academic paper published on Thursday says.Reuters Health Information
Condition: Autism Spectrum Disorder Interventions: Drug: Balovaptan; Drug: Placebo Sponsor: Hoffmann-La Roche Not yet recruiting
Outfielder Tarik El-Abour—who was diagnosed with autism at age 3—recently signed with the Kansas City Royals. El-Abour joined the team for spring training and is playing in the club’s minor league. Several news outlets, along with the Kansas City Royals’ website, state that El-Abour is the first professional baseball player diagnosed with autism. We have signed outfielder Tarik El-Abour to a minor league contract. El-Abour has handled the challenges presented by autism now earning the opportunity to become a professional baseball player. His signing announcement coincides with tonight's Autism ...
[Citizen] Arusha -A day care centre for children suffering from autism is seeking land to expand its activities.
Autism Research, EarlyView.
Schizophrenia (SZ) is a severe neuropsychiatric disorder characterized by psychotic behavior, dysfunction in normal affective responses and altered cognitive functioning. Copy number variants (CNVs), have been verified as an essential factor involved in the pathogenesis of SZ. Among the pathogenic CNVs, the 16p11.2 loci are a hot spot associated with autism-spectrum disorders and mental retardation as well as being candidate loci for SZ (Hanson et al., 2015). Duplications in this region have been determined to be associated with bipolar disorder, SZ, and autism (McCarthy et al., 2009).
Conclusions These findings suggest that sex-based differences in SF for boys and girls with ASD are yet to be determined and appear to be restricted to a relatively small section of SF behaviours related to movement. Possible explanations for these differences and implications for clinical practice are discussed.
Escalating prevalence of autism spectrum disorders (ASD) in recent decades has triggered increasing efforts in understanding roles played by environmental risk factors as a way to address this widespread publi...