Effect of puerarin on collagen metabolism of fibroblasts in pelvic tissue of women with pelvic organ prolapse.

In conclusion, the present study demonstrated evidence increased degradation of the extracellular matrix in pelvic tissues of patients with POP compared with controls, and the protective effect of puerarin against POP via its anti‑degradation effect on collagen. These results provide evidence for puerarin as a novel approach for the treatment of POP.
PMID: 29207080 [PubMed - as supplied by publisher]

Source: Molecular Medicine Reports - December 6, 2017 Category: Molecular Biology Tags: Mol Med Rep Source Type: research