Research finds new ways to fight the opioid crisis

(American College of Neuropsychopharmacology) In the US alone, more than 2 million people struggle with opioid use disorders. Opioids, often prescribed as pain medications, have now become the country's leading cause of drug overdose. But scientists are identifying ways to help combat the epidemic, which include getting people treatment faster, developing safer opioids, and helping patients choose appropriate treatment. A number of recent breakthroughs are being presented at the upcoming conference of the American College of Neuropsychopharmacology.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news

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New England Journal of Medicine, Ahead of Print.
Source: New England Journal of Medicine - Category: Internal Medicine Authors: Source Type: research
As a primary care doctor who cares for many patients with opioid-use disorder, I am invested in timely and effective strategies to curb our nation’s opioid epidemic. Because so many instances of opioid addiction and overdoses begin with or involve commonly prescribed opioids, we need multiple strategies that address the significant harms associated with prescription opioids. I am skeptical of one strategy, however: The President’s Commission and the Food and Drug Administration are promoting development of abuse-deterrent prescription opioids as the solution to our opioid problem. These technologies t...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Meds Medications Pain Management Source Type: blogs
Opioid use has reached epidemic proportions over the past decade, becoming one of America’s highest-priority public health issues. With opioid abuse spiraling out of control, lawmakers, regulators, and health professionals are scrambling to better understand key drivers of this issue and develop an effective action plan. Although the devastating impact of opioids on families and communities is well known, less focus has been given to how it affects the workplace and the role that employers and health care plan sponsors can play in combating it. Opioids’ impact on America’s workforce Opioid use is surging ...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Policy Pain Management Public Health & Source Type: blogs
The increased use of opioid pain medications in North America in the last 2 decades has given rise an epidemic of addictions, overdoses and deaths, to which both the US and Canadian governments have enacted strategies to help combat these crises [1-3]. While these strategies develop multiple interventions to curb opioid use, a common target is to reduce physician opioid prescribing. Many patients may receive their first dose of opioid in the Emergency Department (ED), and recent studies show that there has been a steady increase in opioid prescribing in US EDs to adults (relative increase of 49% from 2001 to 2010) [4, 5].
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Correspondence Source Type: research
Publication date: May–June 2018Source: EXPLORE, Volume 14, Issue 3Author(s): Heather Tick, Arya Nielsen, Kenneth R. Pelletier, Robert Bonakdar, Samantha Simmons, Ronald Glick, Emily Ratner, Russell L. Lemmon, Peter Wayne, Veronica Zador, The Pain Task Force of the Academic Consortium for Integrative Medicine and HealthABSTRACTMedical pain management is in crisis; from the pervasiveness of pain to inadequate pain treatment, from the escalation of prescription opioids to an epidemic in addiction, diversion and overdose deaths. The rising costs of pain care and managing adverse effects of that care have prompted action ...
Source: EXPLORE: The Journal of Science and Healing - Category: Complementary Medicine Source Type: research
Publication date: Available online 1 August 2017Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Patrick H. Finan, Bethany Remeniuk, Kelly E. DunnAbstractProblematic prescription opioid use is cited as a primary contributor to the current ‘opioid epidemic’ in the United States, which is characterized by recent rapid increases in individuals seeking treatment for opioid dependence and staggering rates of opioid overdose deaths. Individuals with chronic pain are commonly prescribed opioids to treat pain, and by this mere exposure are at increased risk for the development of problem...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 18 February 2018Source: Neuroscience LettersAuthor(s): Marta FilizolaAbstractHaving accidental deaths from opioid overdoses almost quadrupled over the past fifteen years, there is a strong need to develop new, non-addictive medications for chronic pain to stop one of the deadliest epidemics in American history. Given their potentially fewer on-target overdosing risks and other adverse effects compared to classical opioid drugs, attention has recently shifted to opioid allosteric modulators and G protein-biased opioid agonists as likely drug candidates to prevent and/or reverse opioid over...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Introduction: Disinformation and Stealth Marketing CampaignsBack in the distant past the US government made some attempt to hold big health care corporations to account for misleading marketing practices.  We learned a lot about these practices from documents revealed in the resulting litigation, and in particular, about stealthy, deceptive systematicmarketing,lobbying, andpolicy advocacy campaigns on behalf of big health care organizations, often pharmaceutical, biotechnology and medical device companies.  For example, in 2012 wefound out about the stealth marketing campaign used by GlaxoSmithKline to sell its a...
Source: Health Care Renewal - Category: Health Management Tags: deception disinformation narcotics perverse incentives propaganda public relations Purdue Pharma stealth marketing Source Type: blogs
Conclusions This study provides evidence supporting the role of OxyContin reformulation in the reduction of onset of OxyContin nonmedical and extra-medical use. PMID: 29978755 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Publication date: May–June 2018Source: EXPLORE, Volume 14, Issue 3Author(s): Heather Tick, Arya Nielsen, Kenneth R. Pelletier, Robert Bonakdar, Samantha Simmons, Ronald Glick, Emily Ratner, Russell L. Lemmon, Peter Wayne, Veronica Zador, The Pain Task Force of the Academic Consortium for Integrative Medicine and HealthABSTRACTMedical pain management is in crisis; from the pervasiveness of pain to inadequate pain treatment, from the escalation of prescription opioids to an epidemic in addiction, diversion and overdose deaths. The rising costs of pain care and managing adverse effects of that care have prompted action ...
Source: EXPLORE: The Journal of Science and Healing - Category: Complementary Medicine Source Type: research
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