99m Tc-rituximab as a tracer for sentinel lymph node biopsy in breast cancer patients: a single-center analysis

ConclusionsARR of SLNB-negative patients with99mTc-rituximab is low. Abnormal axillary ultrasound with negative FNA, not receiving radiotherapy, and age  ≤ 40 years were prognostic factors for higher ARRs.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research

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This article summarises the information that should be provided to women and referring physicians about breast ultrasound (US). After explaining the physical principles, technical procedure and safety of US, information is given about its ability to make a correct diagnosis, depending on the setting in which it is applied. The followingdefinite indications for breast US in female subjects are proposed: palpable lump; axillary adenopathy; first diagnostic approach for clinical abnormalities under 40 and in pregnant or lactating women; suspicious abnormalities at mammography or magnetic resonance imaging (MRI); suspicious ni...
Source: Insights into Imaging - Category: Radiology Source Type: research
In this study, we aim to compare physical examination and ultrasound of axilla and FNAC and assess their accuracy in preoperative staging of axilla. This was a prospective observational study. Patients with biopsy-proven in vasive early-stage breast carcinoma, consenting to be part of the study, underwent ultrasound (US) of ipsilateral axilla with guided FNAC, when indicated and underwent surgery which included complete axillary dissection. Postoperative histopathology was compared to preoperative US and guided cytolog y (if done), to correlate the latter’s efficacy in detecting positive axillary nodes. Clinically, 9...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Authors: Bhandari A, Xia E, Wang Y, Sindan N, Kc R, Guan Y, Lin YL, Wang X, Zhang X, Wang O Abstract Comparing diagnostic accuracy study between ultrasonography (US) guided fine-needle aspiration biopsy (FNAB) and core-needle biopsy (CNB) of the Sentinel lymph nodes (SLNs) in newly diagnosed invasive breast cancer patients. We selected 289 newly diagnosed invasive breast cancer patients from June 2015 to July 2017. Ultrasound (US) guided fine-needle aspiration cytology (FNA) and core-needle biopsy (CNB) was performed to identify patients with suspicious sentinel lymph node (SLN). Patients with a cortical thickness&...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Publication date: July 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 7Author(s): Geok Hoon Lim, Vidya S. Upadhyaya, Hannah Angela Acosta, Jayne Michelley Adolfo Lim, John C. Allen, Lester Chee Hao LeongAbstractBackgroundZ0011 trial showed that early breast cancer patients with low axillary nodal burden, may be spared an axillary lymph node dissection with no survival compromise. Axillary lymph node dissection can be reserved for patients with a high axillary nodal burden. We aim to determine the preoperative factors that could distinguish between low and high axillary nodal burden in Z0011 eligible pa...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
ConclusionUltrasound-guided wire localization of the target lymph node is not suitable for clinical practice because of limitations regarding clip visibility and selective surgical preparation of the target lymph node. Further prospective evaluation of alternative techniques is needed.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Publication date: July 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 7Author(s): Geok Hoon Lim, Vidya S. Upadhyaya, Hannah Angela Acosta, Jayne Michelley Adolfo Lim, John C. Allen, Lester Chee Hao LeongAbstractBackgroundZ0011 trial showed that early breast cancer patients with low axillary nodal burden, may be spared an axillary lymph node dissection with no survival compromise. Axillary lymph node dissection can be reserved for patients with a high axillary nodal burden. We aim to determine the preoperative factors that could distinguish between low and high axillary nodal burden in Z0011 eligible pa...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
ConclusionUltrasound-guided wire localization of the target lymph node is not suitable for clinical practice because of limitations regarding clip visibility and selective surgical preparation of the target lymph node. Further prospective evaluation of alternative techniques is needed.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Abstract BACKGROUND: Axillary lymph node status remains a significant prognostic indicator in breast cancer. Here, the diagnostic accuracy of ultrasound-guided fine-needle aspiration (US-FNA) and ultrasound-guided core needle biopsy (US-CNB) in axillary staging was compared. METHODS: A comprehensive search was undertaken of all published studies comparing the diagnostic accuracy of US-CNB and US-FNA of axillary lymph nodes in breast cancer. Studies were included if raw data were available on the diagnostic performance of both US-FNA and US-CNB, and compared with final histology results. Relevant data were ext...
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
DiscussionUse of AUS may help to tailor patient care without leading to overutilization of ALND, as long as neoadjuvant chemotherapy is administered when appropriate.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Conclusions: EBUS-TBNA is a useful tool for evaluating mediastinal lymphadenopathy in patients with a history of breast cancer and can provide information on the concordance of receptors status between the primary tumor and metastatic sites in the thorax.
Source: Journal of Bronchology and Interventional Pulmonology - Category: Respiratory Medicine Tags: Original Investigations Source Type: research
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