99m Tc-rituximab as a tracer for sentinel lymph node biopsy in breast cancer patients: a single-center analysis

ConclusionsARR of SLNB-negative patients with99mTc-rituximab is low. Abnormal axillary ultrasound with negative FNA, not receiving radiotherapy, and age  ≤ 40 years were prognostic factors for higher ARRs.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research

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Dr Lowenfels reviews a study that compares diagnostic accuracy of ultrasound-guided fine-needle aspiration and ultrasound-guided core-needle biopsy for axillary staging in breast cancer.Medscape General Surgery
Source: Medscape Today Headlines - Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news
Rationale: Breast cancer metastasis to the esophagus is uncommon. To our knowledge, the present case is the first report of breast cancer with dysphagia as the initial symptom. Patient concerns: A 62-year-old woman was admitted to our hospital for progressive dysphagia. Diagnoses: Endoscopic ultrasound-guided fine needle biopsy of the esophageal lesion found poorly differentiated carcinoma, and surgical resection of the breast nodule revealed invasive ductal carcinoma. Interventions: The patient underwent an esophagectomy, and the immunohistochemistry of surgical specimen was identified as metastatic breast canc...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
ConclusionsUS-FNA is a reliable method for diagnosing axillary recurrence in patients with a history of breast cancer.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
ConclusionAlthough clinical and radiological findings of patients with GM may mimic those of breast carcinoma, our study showed that women of childbearing age, especially among Hispanic ethnicity with a recent history of pregnancy or high prolactin level and newly tender mass-like lesion, in addition to new focal asymmetry on mammogram and heterogeneous hypoechoic irregular-shaped mass on ultrasound exam, should raise concern for GM. Non-invasive approach and clinical follow-up were the preferred treatment method.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
ConclusionFNAC with gamma probe and US guidance is not able to correctly detect metastases in the SN and is therefore not able to replace SLNB. Gamma probe-guided US is a highly accurate method for correctly identifying the SN, which offers possibilities for future research.
Source: European Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research
AbstractThe internal mammary lymph node (IMLN) chain is a pathway through which breast lymphatic drainage flows. The internal mammary lymphatic vessel runs around the internal mammary artery and veins with IMLN in the parasternal intercostal spaces. IMLN metastasis, which forms a part of clinical TNM staging, may negatively affect the prognosis of primary breast cancer patients. IMLN metastasis is clinically detected using ultrasound, computed tomography, magnetic resonance imaging, and18F-deoxyglucose positron emission tomography computed tomography. The uptake of radioactive tracers in IMLN with clinically negative axill...
Source: Japanese Journal of Radiology - Category: Radiology Source Type: research
Conclusion: This study confirms that the MG and ultrasound (USG) when combined have significantly higher sensitivity and NPV than observed for a single modality in detecting the both benign and malignant lesions of the breast.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
Most breast cancer patients have some type of surgery to take out their tumors. But that is not sufficient to ensure that all cancer cells are found and removed. “Cancer cells primarily use the lymphatic system to spread throughout the body and are most like to be found in the first draining lymph node, as the node filters out these cells,” said Mathew Stephens, commercial director, Endomag, in an interview with MD+DI. “These ‘sentinel’ nodes are the most likely place to find cancer, and so the surgeon will want to be able...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
ConclusionFNAC with gamma probe and US guidance is not able to correctly detect metastases in the SN and is therefore not able to replace SLNB. Gamma probe-guided US is a highly accurate method for correctly identifying the SN, which offers possibilities for future research.
Source: European Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research
ConclusionAlthough clinical and radiological findings of patients with GM may mimic those of breast carcinoma, our study showed that women of childbearing age, especially among Hispanic ethnicity with a recent history of pregnancy or high prolactin level and newly tender mass-like lesion, in addition to new focal asymmetry on mammogram and heterogeneous hypoechoic irregular-shaped mass on ultrasound exam, should raise concern for GM. Non-invasive approach and clinical follow-up were the preferred treatment method.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
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