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Artificial ovary may fine-tune treatment for menopause symptoms

Many women experiencing menopause have mood swings, forgetfulness and weight gain. Could an implant be a safer alternative to hormone replacement therapy?
Source: New Scientist - Health - Category: Consumer Health News Source Type: research

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CONCLUSIONS: Currently, there is insufficient high-quality evidence to inform women considering HRT after treatment for endometrial cancer. The available evidence (both the single RCT and non-randomised evidence) does not suggest significant harm, if HRT is used after surgical treatment for early-stage endometrial cancer. There is no information available regarding use of HRT in higher-stage endometrial cancer (FIGO stage II and above). The use of HRT after endometrial cancer treatment should be individualised, taking account of the woman's symptoms and preferences, and the uncertainty of evidence for and against HRT use. ...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
We examined the medical records of menopausal women aged between 45 and 79 years from Taiwan's National Health Insurance Research Database of records between 1 January 2000 and 31 December 2010 to establish matched cohorts (13,920 HRT users and 41,760 nonusers). The incidence of tinnitus in HRT users and nonusers were matched 1:3 based on propensity-score matching over this ten year period. The Cox regression hazard model was used to identify risk factors of tinnitus, and results indicate that a significantly lower percentage of HRT users (P = 0.017) developed tinnitus in comparison with nonusers (0.43%, 60/13, 920 vs. 0.5...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
(Natural News) Did you know that a nutrient that can benefit millions of women in the U.S. can be found in soybeans? To date, at least 40 million women in the country aged 51 and above are thinking of undergoing hormone replacement therapy (HRT) to address menopausal symptoms. However, HRT comes with various health risks. The pill-based solution...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Conclusions Supplementation with soy protein with isoflavones for 6 months significantly improved CVR markers and calculated CVR at 6 months during early menopause compared to soy protein without isoflavones. ISRCTN registry ISRCTN34051237.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
This article covers the main presenting complaints and treatments, from lifestyle to hormone replacement therapy, by drawing on guidelines from national bodies.
Source: Nursing Clinics of North America - Category: Nursing Authors: Source Type: research
BackgroundDuring menopause women experience vasomotor and psychosexual symptoms that cannot entirely be alleviated with hormone replacement therapy (HRT). Besides, HRT is contraindicated after breast cancer. ObjectivesTo review the evidence on the effectiveness of psychological interventions in reducing symptoms associated with menopause in natural or treatment‐induced menopausal women. Search strategyMedline/Pubmed, PsycINFO, EMBASE and AMED were searched until June 2017. Selection criteriaRandomised controlled trials (RCTs) concerning natural or treatment‐induced menopause, investigating mindfulness or (cognitive‐)...
Source: BJOG: An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: Systematic Review Source Type: research
Abstract BACKGROUND: During menopause women experience vasomotor and psychosexual symptoms that cannot entirely be alleviated with hormone replacement therapy (HRT). Besides, HRT is contraindicated after breast cancer. OBJECTIVES: To review the evidence on the effectiveness of psychological interventions in reducing symptoms associated with menopause in natural or treatment-induced menopausal women. SEARCH STRATEGY: Medline/Pubmed, PsycINFO, EMBASE and AMED were searched until June 2017. SELECTION CRITERIA: Randomised controlled trials (RCTs) concerning natural or treatment-induced menopause, invest...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: BJOG Source Type: research
BOSTON (CBS) — Scientists at Imperial College London have developed a new class of experimental drugs to treat menopausal hot flashes. In a clinical trial involving 37 women, the compound called MLE4901 reduced the number of hot flashes by almost three-quarters and significantly reduced the severity. The drug blocks a chemical in the brain called neurokinin B and in the study the drug also improved sleep and concentration during the 4-week study period. MLE4901 can affect liver function but two similar drugs which don’t have this side effect are being studied in larger patient trials including one in the U.S. t...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Healthwatch Local News Seen On WBZ-TV Syndicated Local Dr. Mallika Marshall Menopause Women's Health Source Type: news
Taking hormone replacement therapy during menopause may improve the structure and function of women's hearts, potentially lowering their risk of heart disease, say UK investigators.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news
According to a study, published inPLOS ONE, hormone replacement therapy (HRT) has a protective effect on the cardiovascular health of menopausal women.Science Daily
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
More News: Health | Hormone Replacement Therapy | Hormones | Men | Menopause | Ovaries | Women