FDA Approves Semaglutide for Type 2 Diabetes FDA Approves Semaglutide for Type 2 Diabetes
The once-weekly GLP-1 agonist joins a crowded field, but may offer advantages over competitors.FDA Approvals
Publication date: November 2017 Source:Biomedical and Environmental Sciences, Volume 30, Issue 11 Author(s): Guo Qing ZHUANG, You Xin WANG
The increasing number of people with chronic diseases challenges workforce capacity. Type 2 diabetes (T2D) can have work-related consequences, such as early retirement. Laws of most high-income countries requi...
AbstractObesity represents a continuously growing global epidemic and is associated with the development of type 2 diabetes mellitus. The etiology of type 2 diabetes is related to the resistance of insulin-sensitive tissues to its action leading to impaired blood glucose regulation. Photobiomodulation (PBM) therapy might be a non-pharmacological, non-invasive strategy to improve insulin resistance. It has been reported that PBM therapy in combination with physical exercise reduces insulin resistance. Therefore, the aim of this study was to investigate the effects of PBM therapy on insulin resistance in obese mice. Male Swi...
Transcription factor 19 (TCF19) has been reported as a type 1 diabetes–associated locus involved in maintenance of pancreatic β cells through a fine-tuned regulation of cell proliferation and apoptosis. TCF19 also exhibits genomic association with type 2 diabetes, although the precise molecular mechanism remains unknown. It harbors both a plant homeodomain and a forkhead-associated domain implicated in epigenetic recognition and gene regulation, a phenomenon that has remained unexplored. Here, we show that TCF19 selectively interacts with histone 3 lysine 4 trimethylation through its plant homeodomain finger. Kn...
Shipra Bhansali, Anil Bhansali, Rama Walia, Uma Nahar Saikia, Veena Dhawan
Researchers from Bethel University in Minnesota studied people who have or are at risk of type 2 diabetes. Those on a low carb diet saw significantly better results than those on a standard diet.
Authors: Shan PF, Li Q, Khamaisi M, Qiang GF PMID: 29230243 [PubMed]
CPSTF recommends the use of diabetes self-management mobile phone applications (apps), when implemented in healthcare systems, to improve blood glucose among patients with type 2 diabetes.
Conclusions The pancreatic exocrine SP is a potential reservoir of adult stem/progenitor cells, consistent with previous evidence that such cells are duct-derived and express CD133.