Exploring the Moderating Effects of Cognitive Abilities on Social Competence Intervention Outcomes.

Exploring the Moderating Effects of Cognitive Abilities on Social Competence Intervention Outcomes. Behav Modif. 2018 Jan;42(1):84-107 Authors: Stichter JP, Herzog MJ, Kilgus SP, Schoemann AM Abstract Many populations served by special education, including those identified with autism, emotional impairments, or students identified as not ready to learn, experience social competence deficits. The Social Competence Intervention-Adolescents' (SCI-A) methods, content, and materials were designed to be maximally pertinent and applicable to the social competence needs of early adolescents (i.e., age 11-14 years) identified as having scholastic potential but experiencing significant social competence deficits. Given the importance of establishing intervention efficacy, the current paper highlights the results from a four-year cluster randomized trial (CRT) to examine the efficacy of SCI-A (n = 146 students) relative to Business As Usual (n = 123 students) school-based programming. Educational personnel delivered all programming including both intervention and BAU conditions. Student functioning was assessed across multiple time points, including pre-, mid-, and post-intervention. Outcomes of interest included social competence behaviors, which were assessed via both systematic direct observation and teacher behavior rating scales. Data were analyzed using multilevel models, with students nested within schools. Results suggested after controlling for baseline be...
Source: Behavior Modification - Category: Psychiatry & Psychology Authors: Tags: Behav Modif Source Type: research

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Authors: Shafiq S, Pringsheim T Abstract INTRODUCTION: Antipsychotic use in children has increased over the past two decades. Randomized controlled trials have evaluated the efficacy of antipsychotics in autism spectrum disorder (ASD) and disruptive behavior disorders (DBD). Areas covered: The authors systematically analyze the results of randomized controlled trials of second and third generation antipsychotics for irritability in ASD and aggressive and disruptive behavior in DBD with or without low IQ and ADHD. The aim of the review is to assist healthcare professionals to optimize therapy in this population. Exp...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Publication date: Available online 14 August 2018Source: Journal of Neuroscience MethodsAuthor(s): Matthew S. Binder, Christian J. Hernandez-Zegada, Christian T. Potter, Nolan O. Suzanne, Joaquin N. LugoAbstractAlterations in early-life communicative behaviors are a common feature of neurodevelopmental conditions such as autism and epilepsy. One method of investigating communication in murine models is through analyzing ultrasonic vocalizations. These vocalizations are commonly recorded with either the Avisoft or the Ultravox recording programs. However, since no study has compared whether the systems are equally sensitive...
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research
ConclusionsAlterations in F-actin polymerization and WRC have been found in a number of genetic subgroups of IDD and ASD. Thus, LS, a very rare genetic condition, is linked to a more expansive family of genes responsible for neurodevelopmental disorders that have shared pathogenic features.
Source: Molecular Autism - Category: Molecular Biology Source Type: research
In this study, we evaluate the usefulness of nine biomarkers and their association (combination) in predicting ASD onset and development. Data were analyzed using multiple independent mathematical and statistical approaches to verify the suitability of obtained results as predictive parameters. All biomarkers tested appeared useful in predicting ASD, particularly vitamin E, glutathione-S-transferase, and dopamine. Combining biomarkers into profiles improved the accuracy of ASD prediction but still failed to distinguish between participants with severe versus mild or moderate ASD. Library-based identification was effective ...
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 14 August 2018Source: Neurochemistry InternationalAuthor(s): Lindsay Joy Spielman, Deanna Lynn Gibson, Andis KlegerisAbstractThe number of bacterial cells living within the human body is approximately equal to, or greater than, the total number of human cells. This dynamic population of microorganisms, termed the human microbiota, resides mainly within the gastrointestinal tract. It is widely accepted that highly diverse and stable microbiota promote overall human health. Colonization of the gut with maladaptive and pathogenic microbiota, a state also known as dysbiosis, is associated wit...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
This article reviews the biological origins of the social function deficit associated with autism spectrum disorder and the drug therapies with the potential to treat this deficit. A review of the history of autism demonstrates that a deficit in social interaction has been the defining feature of the concept of autism from its conception. Abnormalities identified in early social skill development and an overview of the pathophysiology abnormalities associated with autism spectrum disorder are discussed as are the abnormalities in brain circuits associated with the social function deficit. Previous and ongoing clinical tria...
Source: CNS Drugs - Category: Neurology Source Type: research
AbstractIdentification of autism spectrum disorder (ASD) has been occurring at earlier ages, leading to a need for interventions that suit this age range. Because young children ’s development is highly dependent on adults and positive adult relationships, fields that traditionally have success in treating ASD, such as Applied Behavior Analysis (ABA), must explicitly consider relationships. At the same time, Infant/Early Childhood Mental Health (I/ECMH) specialists that h ave traditionally focused on the parent and child relationship must recognize the importance of addressing atypical or difficult child behavior as ...
Source: Review Journal of Autism and Developmental Disorders - Category: Child Development Source Type: research
AbstractDepression has long been a clinical concern in youth with autism, yet systematic research examining its prevalence, presentation, and treatment has only begun to emerge more recently. Using the search termsautism,asd, orautistic anddepression,depressive,dysthymia, ordysthymic, this systematic review identified 43 articles focused on symptoms of depression in children and adolescents with autism spectrum disorders published between 2012 and 2016. The results of the review indicate that depression is more common in youth with autism spectrum disorders than in typically developing youth and is associated with a multit...
Source: Review Journal of Autism and Developmental Disorders - Category: Child Development Source Type: research
Conclusions Critical gaps in the literature are highlighted. Research in this area is especially limited for Down syndrome and fragile X syndrome. Future directions for taking learning theories into account in interventions for children with intellectual disability are discussed, with a focus on the importance of language input.
Source: Language, Speech, and Hearing Services in Schools - Category: Audiology Source Type: research
Conclusions This finding replicates and extends prior work on verb learning in children with ASD by demonstrating that they can attend to a novel verb's syntactic distribution absent relevant visual or social context, and they can use this information to assign the novel verb an appropriate meaning. We discuss points for future research, including examining individual differences that may impact success and contrasting social and nonsocial word-learning tasks directly.
Source: Language, Speech, and Hearing Services in Schools - Category: Audiology Source Type: research
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