Contiguous verrucous proliferations in syringocystadenoma papilliferum: a retrospective analysis with additional evaluation via mutation ‐specific BRAF V600E immunohistochemistry

Abstract
Syringocystadenoma papilliferum (SCAP) is a benign adnexal neoplasm with apocrine differentiation.1,2 which may be derived from pluripotent cells.3 The lesion may develop within a pre‐existing nevus sebaceus, but the majority of cases arise sporadically.3 Congenital lesions in a Blaschkoid distribution have also been reported, and these cases are thought to represent genetic mosaicism.4,5,6 The tumor has a varied clinical appearance, but typically presents as a raised warty, hairless plaque or nodule.3

Source: Journal of Cutaneous Pathology - December 1, 2017 Category: Pathology Authors: BJ Friedman, J Sahu, CC Solomides, DM Connolly, JB Lee Tags: ORIGINAL ARTICLE Source Type: research