Insights into the bisphosphonate holiday: a preliminary FTIRI study

ConclusionsDiscontinuation of alendronate for 5 years did not affect key FTIRI parameters, supporting the hypothesis that discontinuation would have little impact on bone composition. Modest differences were observed in three parameters that are not likely to affect bone mechanical properties. These preliminary data suggest that a 5-year BP hol iday is not harmful to bone composition.

http://link.springer.com/10.1007/s00198-017-4324-5

Source: Osteoporosis International - December 5, 2017 Category: Orthopaedics Source Type: research