Primary cutaneous secretory carcinoma: a previously overlooked low grade sweat ‐gland carcinoma
Abstract
Twelve cases of primary cutaneous secretory carcinoma (PCSC) have been published; nine of them showed the ETV6‐NTRK3 translocation and an additional case had a heterozygous deletion of ETV6 in 25% of cells (Table 1).1‐7 These cutaneous tumors are related to secretory breast carcinoma (SBC) and mammary analogue secretory carcinoma (MASC) from the salivary glands, with all sharing a balanced chromosomal translocation of t(12;15)(p13;q25) that leads to ETV6‐NTRK3 gene fusion.
Source: Journal of Cutaneous Pathology - Category: Pathology Authors: M. Llamas ‐Velasco, T. Mentzel, A. Rütten Tags: CASE REPORT Source Type: research
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