A woman with a transplanted uterus just gave birth — a first for the U.S.

For women with uterine factor infertility who want to be mothers, the calculus has always been heartbreakingly simple: No uterus means no pregnancy. The equation changed drastically in 2014, when Swedish doctors delivered a healthy 3.9-pound baby that was the result of a successful uterus transplant. Now, doctors at Baylor University say a woman born […]Related:A model tattooed her eyeball purple. She now could lose her eye.A man collapsed with ‘Do Not Resuscitate’ tattooed on his chest. Doctors didn’t know what to do.A man claims he went down a ‘Raging Rapids’ ride — and came out with an eye-eating parasite
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 17 September 2018Source: Neurobiology of StressAuthor(s): Sarah R. Horn, Leslie E. Roos, Elliot T. Berkman, Philip A. FisherAbstractEarly life adversity is a documented risk factor for substance abuse and addiction. The pre- and perinatal period (i.e., from implantation, through pregnancy, to 6 months of age) is a critical period marked by high biological plasticity and vulnerability, making perinatal stress a particularly robust form of adversity. The neuroendocrine and immune systems are key mechanisms implicated in the transmission of addiction risk. We review animal and human studies ...
Source: Neurobiology of Stress - Category: Neuroscience Source Type: research
Publication date: Available online 18 September 2018Source: Parasitology InternationalAuthor(s): Boye Liu, Zhuqing Deng, Wei Huang, Lu Dong, Yanyun ZhangAbstractAvian haemosporidian parasites are highly diverse, have a wide range of host specificity, and reveal diverse compatibility with regard to host range and geographical distribution. Therefore, understanding haemosporidian parasite diversity in different host species and different regions is crucial. A survey of the haemosporidian parasite in 186 Godlewski's buntings in Beijing was conducted to compare infection patterns between Godlewski's bunting, local passerines a...
Source: Parasitology International - Category: Parasitology Source Type: research
Publication date: October 2018Source: Molecular and Biochemical Parasitology, Volume 225Author(s): Dana Ditgen, Emmanuela M. Anandarajah, Anika Reinhardt, Abuelhassan Elshazly Younis, Susanne Witt, Jan Hansmann, Eva Lorenz, Marisela García-Hernández, Daniela Paclik, Hanns Soblik, Abbas Jolodar, Peter H. Seeberger, Eva Liebau, Norbert W. BrattigAbstractHelminths are complex pathogens that ensure their long-term survival by influencing the immune responses of their host. Excretory/secretory products (ESP) can exert immunoregulatory effects which foster parasite survival. Galectins represent a widespread group o...
Source: Molecular and Biochemical Parasitology - Category: Parasitology Source Type: research
Authors: Czemerska M, Robak T, Wierzbowska A Abstract INTRODUCTION: Acute myeloid leukemia (AML) remains a poor prognosis hematological malignancy. The introduction of aggressive chemotherapy with allogeneic stem cell transplantation has resulted in improved clinical outcomes in younger patients. However, the treatment results in unfit elderly AML population remain disappointing. New strategies should be introduced to improve the prognosis in this group of patients. Areas covered: This review presents and discusses the mechanism of action, safety and efficacy of sapacitabine in AML patients. Expert opinion: Sapacit...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Authors: Daniels LM, Kufel WD Abstract INTRODUCTION: Clostridium difficile infection (CDI) has become a significant healthcare-associated infection and is strongly associated with antibiotic use. Practice guidelines have recently been revised incorporating updated recommendations for diagnosis, treatment, and prevention. Areas Covered: This review discusses updated aspects of CDI management. New and emerging pharmacologic options for treatment and prevention are reviewed. Expert opinion: Metronidazole is associated with lower rates of treatment success compared to vancomycin and should no longer be used as primary ...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Scientists warn that soot from polluted air is reaching the placenta of pregnant women ‚Äč, and could possibly harm the health of unborn babies
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
In this study, healthy C57BL/6 J mice were used to establish an animal model of maternal exposure to traffic pollutant during pregnancy, and the toxic effects on the reproductive system of F2 male mice were analysed using mRNA and miRNA microarray. Our results showed that 54 miRNAs and 1927 mRNAs were significantly altered in the exposed group. Gene Ontology (GO) analysis revealed that the most significant GO terms for biological process, molecular function and cellular component were myeloid cell differentiation, growth factor binding and main axon. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis de...
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research
ConclusionsTransfusions are prevalent in the perioperative period after pediatric kidney transplantation. Lower pre-transplant hemoglobin increases the risk of transfusion. Graft function predicts hemoglobin levels at 3  months.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsAlthough we do not have a control group, we may speculate that patients who received treatment returned to a “standard” condition possibly improving final outcome. Protocol biopsies are a powerful diagnostic tool for the management of pediatric renal transplant recipients. In view of the lack of evidence that biopsies taken 5 years after transplantation lead to any therapeutic change, their use should be reconsidered.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
This study aimed to evaluate plasma concentrations of leptin and total ghrelin in children with chronic kidney disease (CKD) and assess their roles in protein-energy wasting (PEW).MethodsThis study consisted of three different CKD populations [CKD group (20 patients with non-dialysis CKD), dialysis group (39 patients on dialysis), and kidney transplant (KTx) group (35 KTx recipients)] and control group (18 healthy children). Plasma leptin and total ghrelin levels were measured. Multi-frequency bioimpedance analysis was used for the assessment of fat and lean mass. PEW was defined using criteria including body mass, muscle ...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
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