Woman With Transplanted Uterus Gives Birth, the First in the U.S.

A woman born without a uterus had one transplanted from a live donor, and gave birth to a healthy son, at Baylor University Medical Center in Dallas.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Transplants Uterus Baylor University Baby Pregnancy and Childbirth Infertility Cleveland Clinic Source Type: news

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Purpose of review The purpose of this review is to analyze what is known to date about the relation between telomeres and male fertility, and if it is possible for telomeres, or elements related to them, to be used as new prognostic biomarkers in fertility treatment. Recent findings Cells in germ series, including spermatozoids, have longer telomeres (10–20 kb), and do not seem to undergo the shortening that takes place in somatic cells with age as they present telomerase activity. Longer telomere length found in the sperm of older fathers, influences their offspring possessing cells with longer telomere length....
Source: Current Opinion in Obstetrics and Gynecology - Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García-Velasco Source Type: research
Dr. Giuliano Testa, a transplant surgeon at Baylor University Medical Center at Dallas who led the medical team that performed the first successful uterus transplants in the United States, said Tuesday that he hopes “what we are doing is going to shed light on infertility for women.” “I personally never knew it was such a widespread issue,” Testa said at the TIME 100 Gala on Tuesday. “We should be thinking about it not just as a birth, but a wellbeing issue.” Testa attended the TIME 100 Gala after being named by TIME magazine as one of the most influential people in the world for his rol...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime T1002018 Source Type: news
Although cancer remains a critical health concern, significant medical advances in cancer detection and treatment have improved survival rates for patients. In children receiving total body radiation (TBI), bone-marrow transplant (BMT), or cyclophosphamide equivalent dose (CED) of>4,000mg/m2, the risk of infertility is significant. The National Physicians Cooperative (NPC) has published site-specific articles compiling data regarding use of cryopreserved tissue, return of endocrine function, and pregnancy outcomes, however no comprehensive review has been conducted.
Source: Journal of Pediatric and Adolescent Gynecology - Category: OBGYN Authors: Source Type: research
This study presents a summary of the investigations that indicate the key role of stem cell therapy in regeneration and renovation of defective parts.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Although cancer remains a critical health concern, significant medical advances in cancer detection and treatment have improved survival rates for patients. In children receiving total body radiation (TBI), bone-marrow transplant (BMT), or cyclophosphamide equivalent dose (CED) of>4,000mg/m2, the risk of infertility is significant. The National Physicians Cooperative (NPC) has published site-specific articles compiling data regarding use of cryopreserved tissue, return of endocrine function, and pregnancy outcomes, however no comprehensive review has been conducted.
Source: Journal of Pediatric and Adolescent Gynecology - Category: OBGYN Authors: Source Type: research
This study presents a summary of the investigations that indicate the key role of stem cell therapy in regeneration and renovation of defective parts. PMID: 29571018 [PubMed - as supplied by publisher]
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
Hormonal changes, in either men or women experiencing chronic kidney disease (CKD), cause a decreased libido, erectile dysfunction, dysmenorrhea and ovarian dysfunction, all of which may contribute to infertility. Patients could rapidly restore endocrines and sexual function after a successful renal transplantation (RTx), which may assist in achieving a successful pregnancy. However, the fetus will be exposed to the immunosuppressive agents passed on from the female recipients, which may be another potential factor leading to a poor fetal outcome.
Source: Transplantation Proceedings - Category: Transplant Surgery Authors: Source Type: research
Kidney transplantation (KTx) is the treatment of choice in patients with end-stage renal failure. Among various medical issues in female graft recipients, the need for maternity can become an overriding one. Gonadal dysfunction usually resolves within 6 months after transplantation. However, the prevalence of infertility is similar to this in the general population.
Source: Transplantation Proceedings - Category: Transplant Surgery Authors: Source Type: research
A second woman in the U.S. born without a uterus has given birth to a baby, thanks to a uterus transplant. The birth took place at Baylor University Medical Center at Dallas, a part of Baylor Scott &White, which performed the first birth via uterus transplant late last year. The baby, born in February, is a girl. The hospital is not revealing the identity of the mother, but says the pregnancy and birth were uncomplicated. The birth is the second in the hospital’s ongoing uterus transplant clinical trial. The women in the trial have absolute uterine factor infertility (AUI), which means their uterus is nonfunction...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized fertility healthytime onetime Source Type: news
Uterine factor infertility (UFI) affects thousands of women. UFI may be caused by congenital absence of the uterus (Mayer-Rokitansky-Kuster-Hauser or MRKH syndrome), iatrogenic removal of the uterus, or women who have uteri that are in situ but have been damaged by infection of surgical instrumentation (1). Despite advances in assisted reproductive technologies, women with UFI cannot achieve pregnancy, which has led to the development of uterine transplantation (2). In the event that a patient with UFI is approved to undergo uterine transplantation, IVF must first be performed to assure the availability of embryos for tran...
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster presentation Source Type: research
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