Overview of carbon and nitrogen catabolite metabolism in the virulence of human pathogenic fungi

This article is protected by copyright. All rights reserved. Fungal infections that result in the death of immunocompromised subjects have risen steadily over the last few years. The metabolic utilisation of preferred carbon and nitrogen sources, encountered in a host niche‐specific manner, has been shown to be an important virulence determinant. Characterisation of preferred nutrient source utilisation, including sensing and uptake, by pathogenic fungi has only been partially characterised, and further species‐specific elucidation is required, in order to uncover targets for anti‐fungal therapies.
Source: Molecular Microbiology - Category: Microbiology Authors: Tags: Microreview Source Type: research

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