Solitary Aggregatibacter aphrophilus tectal abscess in an immunocompetent patient.

Conclusion: We suggest that an empiric diagnosis of tectal glioma should be made with caution for a ring-enhancing mass. CSF should be routinely cultured at the time of operative diversion if abscess is a possibility. PMID: 29184708 [PubMed]
Source: Surgical Neurology International - Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

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ConclusionDespite the benign histopathology, CGs have high recurrence rates. Morphologically, CGs are solid homogenously enhancing tumors. GTR should be achieved, preferably by the trans-lamina terminalis route. Anatomy and immunohistochemistry seem to show tanycytic origin of this entity.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
This report is the first described case of a diffuse midline glioma H3 K27M-mutant disseminating to the peritoneal cavity via a shunt. A four-year-old female presented with a large solid-cystic lesion centred on the suprasellar cistern, histologically revealed to be diffuse midline glioma H3 K27M-mutant. The patient received multiple courses of radiotherapy to the primary lesion and metachronous spinal metastases, and underwent bilateral ventriculoperitoneal shunts. She presented fourteen months following diagnosis with acute hydrocephalus and massive ascites revealed to be due to histologically confirmed intra-abdominal g...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Alcyone Lifesciences is a medical technology company based out of Lowell, MA, which specializes in central nervous system (CNS) drug delivery platforms for targeted infusions of the brain or spinal cord. Their Thecaflex DRx System was recently awarde...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Neurology Neurosurgery Pain Management Psychiatry Source Type: blogs
AbstractBackgroundCerebrospinal fluid (CSF) circulation disturbances may occur during the course of disease in patients with glioblastoma. Ventriculoperitoneal shunting has generally been recommended to improve symptoms in glioblastoma patients. Shunt implantation for patients with glioblastoma, however, presents as a complex situation and produces different problems to shunting in other contexts. Information on complications of shunting glioma patients has rarely been the subject of investigation. In this retrospective study, we analysed restropectively the course and outcome of glioblastoma-related CSF circulation distur...
Source: Fluids and Barriers of the CNS - Category: Neuroscience Source Type: research
CONCLUSIONS Analysis of this case series shows that a major subpopulation of tectal gliomas show progression and malignant transformation in children as well as in adolescents. These tumors therefore cannot be considered inert lesions and require histological confirmation and close follow-up. Quality-of-life questionnaires show that tectal glioma patients might benefit from special psychological support in emotional, social, and cognitive functionality. PMID: 29852760 [PubMed - in process]
Source: Neurosurgical Focus - Category: Neurosurgery Authors: Tags: Neurosurg Focus Source Type: research
Abstract OBJECTIVE The clinical course of high-grade central nervous system gliomas is occasionally complicated by hydrocephalus. The risks of shunt placement and clinical outcome following CSF diversion in this population are not well defined. METHODS The authors retrospectively reviewed the outcomes of patients with pathologically confirmed WHO grade III or IV gliomas with shunt-treated hydrocephalus at their institution. Outcomes of patients in this cohort were compared with those of patients who underwent shunt treatment for normal pressure hydrocephalus (NPH). Hospital-reported outcomes in a national database...
Source: Journal of Neurosurgery - Category: Neurosurgery Authors: Tags: J Neurosurg Source Type: research
Authors: Zheng J, Chen G, Xiao Q, Huang Y, Guo Y Abstract The present study aimed to investigate the efficacy of endoscopy in the treatment of post-shunt placement for slit ventricle syndrome (SVS). Endoscopic surgery was performed on 18 patients with SVS between October 2004 and December 2012. Sex, age, causes of the hydrocephalus, ventricular size and imaging data were collected and analyzed. All patients were divided into two groups according to ventricular size and underwent endoscopic surgeries, including endoscopic third ventriculostomy (ETV), endoscopic aqueductoplasty and cystocisternostomy. All treated pat...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
CONCLUSIONS The authors provide their experience using a keyhole lobectomy for resecting temporal gliomas. Their data demonstrate the feasibility of using less invasive techniques to safely and aggressively treat these tumors. PMID: 28686118 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - Category: Neurosurgery Authors: Tags: J Neurosurg Source Type: research
Conclusions:These few patients suggest that ventriculomegaly develops insidiously in patients with GBM and that diagnosis is often delayed. We are initiating a larger retrospective study to develop criteria to identify patients at risk for developing hydrocephalus and to identify those who would benefit from VPS.Disclosure: Dr. Miranda has nothing to disclose. Dr. Miller has nothing to disclose. Dr. Andersen has nothing to disclose. Dr. Hatzoglou has nothing to disclose. Dr. DeAngelis has received personal compensation for activities with Juno Therapeutics as a member of the Medical Advisory Board, Sapience and Roche as a ...
Source: Neurology - Category: Neurology Authors: Tags: Neuro-oncology: Gliomas I Source Type: research
We present and discuss a case of chordoid glioma that arose in a 46-year-old female who presented with progressive fatigue, headache, and altered mental status, attributable to severe hydrocephalus caused by a third ventricular mass. She underwent urgent subtotal resection and ventriculo-peritoneal shunt placements. Post-operative MRI noted residual tumor in the anterior resection cavity. An MRI performed 9 weeks later showed substantial progression, with marked tumor enlargement and compression of adjacent hypothalamic structures and the optic chiasm. Despite a course of radiation therapy, the tumor continued to enlarge, ...
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
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