Fixed forced detection for fast SPECT Monte-Carlo simulation.
Fixed forced detection for fast SPECT Monte-Carlo simulation. Phys Med Biol. 2017 Nov 29;: Authors: Cajgfinger T, Rit S, Letang JM, Halty A, Sarrut D Abstract Monte-Carlo simulations of SPECT images are notoriously slow to converge due to the large ratio between the number of photons emitted and detected in the collimator. This work proposes a method to accelerate the simulations based on Fixed Forced Detection (FFD) combined with an analytical response of the detector. FFD is based on a Monte-Carlo simulation but forces the detection of a photon in each detector pixel weighted by the probability of emission (or scattering) and transmission to this pixel. The method was evaluated with numerical phantoms and on patient images. We obtained differences with analog Monte-Carlo lower than the statistical uncertainty. The overall computing time gain can reach up to 5 orders of magnitude. Source code and examples are available in the Gate V8.0 release. . PMID: 29185992 [PubMed - as supplied by publisher]
PP Batchala, PK RehmJournal of Postgraduate Medicine 2019 65(4):237-240 A 66-year-old female underwent preoperative evaluation for primary hyperparathyroidism. Ultrasound (US) neck and technetium (Tc)-99m-sestamibi planar scintigraphy were negative, but single photon emission computed tomography/computed tomography (SPECT/CT) demonstrated a tracer-avid retropharyngeal nodule compatible with parathyroid adenoma (PTA). A retrospective review of CT neck angiogram (CTA) and neck magnetic resonance imaging (MRI) performed 4 months earlier for stroke evaluation revealed arterial phase hyperenhancing retropharyngeal tissue, whic...
AbstractObjectiveQualitative interpretation in bone scan is often complicated by the presence of degenerative joint disease (DJD), especially in the elderly patient. The aim of this study is to compare objectively99mTc-MDP tracer uptake between DJD and osseous metastases of the spine using semi-quantitative assessment with SPECT SUV.MethodsBone scan with SPECT/CT using99mTc-MDP was performed in 34 patients diagnosed with prostate carcinoma. SPECT/CT was performed based on our institutional standard guidelines. SUVmax based on body weight in 238 normal vertebrae visualized on SPECT/CT was quantified as baseline. A total of ...
We present a patient with a cystic thyroid nodule and SThere are number of different peptides or antibodies that have been labelled with 177Lutetium and have been used in imaging and treatment for clinical usage. To our knowlodge, 177Lutetium has never been labelled with macroaggregated albumin (MAA) before. There was special effort exerted in the radiopharmacy laboratory of Istanbul University-Cerrahpaşa, to bind 177Lu with MAA (LUTMA). We present 43-year-old male patient with a cystic thyroid nodule and SPECT/CT imaging after intranodular 177Lutetium labelled macroaggregated albumin injection and a treatment effect of t...
ConclusionOur111In-anti-CDH17 Mab D2101 depicted CDH17-positive gastric cancer xenografts in vivo and has the potential to be an imaging probe for the diagnosis of primary lesions and lymph-node metastasis in gastric cancer.
ConclusionsMyocardial perfusion was recovered by steroid therapy in 61% and preserved in 8% of patients. Myocardial perfusion recovery after steroid therapy was significantly associated with a low incidence of MACE.
In this report, we focus on an inconclusive study case as a potential pitfall of 99mTc-PYP scintigraphy and discuss the interpretation of 99mTc-PYP scintigraphy findings with using both planar and SPECT/CT imaging for improvement of diagnostic accuracy for ATTR cardiac amyloidosis.
To analyse the additional clinical value of protocol-driven and selective use of multidetector single-photon-emission tomography/computed tomography (SPECT/CT) in oncology patients undergoing whole-body bone scintigraphy (BS) and to analyse reporter confidence in diagnosis with and without SPECT/CT.
Conclusions99mTc-aprotinin scintigraphy is valuable for the non-invasive diagnosis of AL cardiac amyloidosis.
Publication date: Available online 5 October 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): L. Filippi, P. Basile, R. Pirisino, O. Schillaci, O. Bagni