Anaesthetic efficacy of 4% articaine compared with 2% mepivacaine: a randomized, double-blind, crossover clinical trial

The aim of this study was to evaluate the clinical efficacy of 4% articaine (Ar4) compared to 2% mepivacaine (Me2), both in combination with 1:100,000 epinephrine, in a unique soft tissue model. This was a randomized, double-blind, crossover clinical trial. The anaesthetic was applied to the lower lip using a computerized local delivery system. The following were evaluated: blood flow, thermal sensation, pressure and proprioception, extent of anaesthesia, gradual elimination, and the final duration of the effect of the anaesthesia.

Source: International Journal of Oral and Maxillofacial Surgery - November 30, 2017 Category: ENT & OMF Authors: M.C. Bortoluzzi, P. de Camargo Smolarek, R. Cecato, M.T. Pochapski, A.C.R. Chibinski Tags: Randomised Controlled Trial Source Type: research