Survival of patients with AIDS and co-infection with the tuberculosis bacillus in the South and Southeast regions of Brazil

Resumo O presente estudo buscou analisar a sobrevida de pacientes com a coinfec ção AIDS-Tuberculose por meio de um estudo de coorte retrospectivo de indivíduos com 13 anos ou mais e diagnóstico de AIDS notificados nos anos de 1998-99 e seguimento de 10 anos. Dos 2.091 casos de AIDS, 517 (24,7%) tinham diagnóstico positivo para tuberculose, sendo 379 (73,3%) masculinos. O risco entre os coinfectados foi 1,65 vezes os não coinfectados. As variáveis associadas à maior sobrevida foram: sexo feminino (HR = 0,63), escolaridade ≥ oito anos (HR = 0,52), crit ério diagnóstico CD4 (HR = 0,64); e à menor sobrevida: faixa etária ≥ 60 anos (HR = 2,33), n ão uso de ARV (HR = 8,62), não investigação para hepatite B (HR = 2,44) e doenças oportunistas ( ≥ duas) (HR = 1,97). A sobreviv ência acumulada foi de 71% nos não coinfectados e 62% nos coinfectados na região Sul e de 74% e 58%, respectivamente, na região Sudeste, 60 meses após o diagnóstico de AIDS. A AIDS e a Tuberculose exigem acompanhamento e adesão ao tratamento e são marcadores da atenção à saúde e da sobre vivência dos pacientes no Brasil.Abstract The study investigates the survival of patients with co-infection AIDS-TB through a retrospective study of a cohort of individuals aged 13 or more and the diagnosis of AIDS...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research

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Roche has expanded the Global Access Program, originally established to increase availability of HIV diagnostics in underserved countries, to include diagnostic tests for tuberculosis, hepatitis, and human papillomavirus (HPV). Increased access to reliable diagnostics will allow early, possibly life-saving, detection and decrease the spread of these diseases. Roche launched the program in 2014 and began offering the added tests in July. The molecular diagnostics available include tests for determination of HIV-1 viral load, early diagnosis of HIV-1 and -2 in young infants, Mycobacterium tuberculosis (MTB) and rifampin/ison...
Source: MDDI - Category: Medical Devices Authors: Tags: IVD Source Type: news
[Monitor] In 2016, deaths caused by viral hepatitis surpassed all chronic infectious diseases, including HIV/Aids, malaria and tuberculosis, according to a Global Burden of Disease study. The prevalence of hepatitis B in Uganda stands at 4.1 per cent, which means that 1.75 million people are infected. This is according to a study carried out by the Ministry of Health in partnership with the Centre for Disease Control (CDC) and the World Health Organisation (WHO).
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
CONCLUSIONS: HIV infection follows the national trend, but hepatitis B and C coinfection rates were higher, while tuberculosis rate was lower.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
This study aimed to analyze characteristics and factors associated with late initiation of ART among HIV-infected treatment-naïve patients. Methods: This cross-sectional study included PLHIV older than 17 years who initiated ART at two public health facilities from 2009 to 2012, in a city located in Midwestern Brazil. Pregnant women were excluded. Data were collected from medical records, antiviral dispensing forms, and the Logistics Control of Medications System (SICLOM) of the Brazilian Ministry of Health. Late initiation of ART was defined as CD4+ cell count
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
In this study, we investigated the immunological changes in the levels of monocytes and Tregs and the associations between these cell types in HIV-1-infected MSM with syphilis. Methods Study Participants We enrolled 81 participants in this study. These individuals were assigned to four groups on the basis of serologic testing and HIV-1 results, namely, the rapid plasma reagin (RPR+) group, the CHI group, the CHI&RPR+ group, and the healthy control group. HIV-1 infection status was determined with the HIV-1/2 antigen/antibody combo enzyme immunoassay (Beijing Wantai Biological Medical Company, Beijing, China). Positive ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Purpose of review Long-acting parenteral drug delivery is an established and widely accepted solution to the problem of poor adherence when daily oral medications are used to treat or prevent chronic medical conditions. Poor adherence to oral formulations remains a major barrier to successfully treating or preventing HIV, tuberculosis (TB), and viral hepatitis. The uptake of long-acting formulations developed for these infections is uncertain, despite their promise. This review addresses the current state of development of long-acting and extended-release approaches to HIV, TB, and viral hepatitis in the context of creat...
Source: Current Opinion in HIV and AIDS - Category: Infectious Diseases Tags: CREATING DEMAND FOR HIV PRODUCTS, DRUGS AND DIAGNOSTICS: Edited by David Ripin and Sharonann Lynch Source Type: research
Conclusions/SignificanceOur work demonstrates a strong association betweenS.mansoni infection and hepatotoxicity among HIV-infected patients on antiretroviral therapy. Our study highlights the importance of schistosome screening and treatment for patients starting antiretroviral therapy in schistosome-endemic settings. Additional studies to determine the effects of schistosome-HIV co-infections are warranted.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
by Karima Chaabna, Sohaila Cheema, Ravinder Mamtani The Gulf Cooperation Council (GCC) countries namely, Bahrain, Kuwait, Oman, Qatar, United Arab Emirates (UAE), and Saudi Arabia, have experienced unique demographic changes. The major population growth contributor in these countries is young migrants, which has led to a shift in the population age pyramid. Migrants constitute the vast proportion of GCC countries’ population reaching>80% in Qatar and UAE. Using Global Burden of Disease Study 2015 (GBD 2015) and United Nations data, for the GCC countries, we assessed the association between age-standardized mortal...
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research
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Source: AIDS Care - Category: Infectious Diseases Authors: Source Type: research
Conclusion The vaccination comprises a misguided and unsafe national health care program which claims to prevent disease. Many significant health injuries are associated with vaccinating adults. Government resources are being spent researching and developing new and different vaccinations. Subjecting adults to more vaccinations is likely to cause more health injury and illness. References: http://www.vaccinationcouncil.org/2012/07/05/herd-immunity… http://www.cdc.gov/chronicdisease/overview/ http://www.vaccinationcouncil.org/2011/02/18/60-lab-studies… http://www.cdc.gov/vaccines/schedules/hcp/adult.html...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Logical Michelle Goldstein Recent Articles Top Stories adult vaccination adult vaccines new vaccines shingles vaccine truth about vaccines Source Type: blogs
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