Optellum, Mirada present lung cancer study at RSNA 2017

Artificial intelligence (AI) software developer Optellum and imaging software...Read more on AuntMinnie.comRelated Reading: Mirada's deep-learning contours match human-drawn contours Optellum unveils lung cancer analysis software Mirada showcases XD:PACS at RSNA 2016 Philips, Mirada sign distribution deal Mirada launches nuclear medicine software at RSNA 2015 Former Philips CEO joins Mirada Medical
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Metabolic dependence of cyclosporine A on cell proliferation of human non‑small cell lung cancer A549 cells and its implication in post‑transplant malignancy. Oncol Rep. 2019 Mar 18;: Authors: Qin X, Chen Z Abstract Cyclosporine A (CsA), a widely used immunosuppressant to prevent organ transplant rejection, is associated with an increased cancer risk following transplantation, particularly in the lung. However, the underlying mechanisms remain unclear. In the present study, using human non‑small cell lung cancer A549 cells, it was determined that CsA (0.1 or 1 µM) promoted ce...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Rayfield Byrd knows when it’s time to wake up every morning. The 68-year-old Oakland, Cal., resident hears a voice from the living room offering a cheery good morning. Except Byrd lives alone. A little after 8 a.m. each day, a small yellow robot named Mabu asks Byrd how he’s doing. Byrd has Type 2 diabetes and congestive heart failure, and about three years ago, he had surgery to implant a microvalve in his heart to keep his blood flowing properly. To stay healthy, he takes four medications a day and needs to exercise regularly. To make sure his heart is still pumping effectively, his doctor needs to stay on to...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Artificial Intelligence Life Reinvented medicine Source Type: news
Authors: Bewersdorf JP, Stahl M, Zeidan AM Abstract INTRODUCTION: Immune system evasion is essential for tumor cell survival and is mediated by the immunosuppressive tumor microenvironment and the activation of inhibitory immune checkpoints. While immune checkpoint-based therapy yielded impressive results in several advanced solid malignancies such as melanoma and non-small cell lung cancer, its role in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) is still evolving. Areas covered: Here we review the immunology in the tumor microenvironment in the bone marrow and discuss the current preclinical an...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
In conclusion, salidroside inhibited the survival, migration and invasion of NSCLC cells. Salidroside blocked AKT and the MEK/ERK signal pathway by upregulating miR-195 expression in A549 cells. PMID: 30880481 [PubMed - in process]
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Volume 47, Issue 1, December 2019, Page 1014-1021 .
Source: Artificial Cells, Blood Substitutes, and Biotechnology - Category: Biotechnology Authors: Source Type: research
In conclusion, circ_0043278 promoted NSCLC cell proliferation, invasion, and migration by increasing ROCK1, CDKN1B, and AKT3 expressions through direct inhibition of miR-520f. PMID: 30873868 [PubMed - in process]
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Volume 47, Issue 1, December 2019, Page 810-821 .
Source: Artificial Cells, Blood Substitutes, and Biotechnology - Category: Biotechnology Authors: Source Type: research
WEDNESDAY, March 13, 2019 -- The term artificial intelligence (AI) might bring to mind robots or self-driving cars. But one group of researchers is using a type of AI to improve lung cancer screening. Screening is important for early diagnosis and...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Conclusion.The use of agents that act on the PD‐L1 pathway are contraindicated in the face of solid organ allografts because of unacceptably high rates of irreversible allograft rejection. It appears that the use of ipilimumab may be tolerated as the mechanism is different from that of the PD‐L1 agents.Implications for Practice.Transplant rejection is a complex process that puts stress on patients and their families and can lead to tragic results. Significant advancements in the field of immunosuppression have led to the engenderment of agents devised to extend the survival of transplant recipients. The advent of immun...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Hepatobiliary, Lung Cancer, Melanoma and Cutaneous Malignancies Immuno ‐ Oncology Source Type: research
We report the case of a patient with ALK translocated ALCL with CNS involvement who developed debilitating neuropathy after chemotherapy and was treated with alectinib at relapse. The patient had a complete response after 6 weeks which has continued for 6 months allowing him to undergo an allogeneic stem cell transplant. To our knowledge, this is the first published case report of a patient with ALCL successfully treated with alectinib.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
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