Imaging the role of inflammation in mood and anxiety-related disorders.

CONCLUSIONS: Neuroimaging effects of inflammation on reward and threat circuitry may be used as biomarkers of inflammation for future development of novel therapeutic strategies to better treat mood and anxiety-related disorders in patients with high inflammation. PMID: 29173175 [PubMed - as supplied by publisher]
Source: Current Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Neuropharmacol Source Type: research

Related Links:

AbstractOnline patient portals may be effective for engaging patients with mental health conditions in their own health care. This retrospective database analysis reports patient portal use among Veterans with mental health diagnoses. Unadjusted and adjusted odds of portal feature use was calculated using logistic regressions. Having experienced military sexual trauma or having an anxiety disorder, post-traumatic stress disorder, or depression were associated with increased odds of portal use; bipolar, substance use, psychotic and adjustment disorders were associated with decreased odds. Future research should examine fact...
Source: Administration and Policy in Mental Health and Mental Health Services Research - Category: Psychiatry Source Type: research
Conclusion: GBP appears to be effective in the treatment of some forms of anxiety disorders, and alcohol withdrawals or dependence, albeit it is effective often as an adjunctive medication rather than as a monotherapeutic agent. More rigorous larger clinical trials are required to resolve the contradictory existing data for the efficacy of GBP. It is worth noticing that numerous clinical studies on this subject are open-label trials, which are inherently less rigorously analyzed. Therefore, more extensive large randomized controlled trials are required to examine not only the effectiveness of GBP but also its safety and tolerance.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
You have depression, or bipolar disorder. And on some days, you feel like you’re treading water—at best. You’re tired of struggling. You’re tired of regularly feeling tired. You’re angry that your to-do list just keeps getting longer and longer. You’re angry that you have to deal with so much darkness day in and day out. Some days are just hard. Some days you feel so overwhelmed. It is on these days that you probably feel like the only person on the planet who’s struggling with persistent symptoms. Thankfully, you’re not. And thankfully, it will get better. We asked individua...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar Depression Disorders General Inspiration & Hope Self-Help Mood Disorder overwhelm peer support Source Type: blogs
It’s hard working as a college professor with bipolar disorder. I suppose it’s hard working anywhere with bipolar disorder, but my particular vocation is teaching 18-year-olds how to write at a local university. I’ve had bipolar illness for almost 30 years now; I was diagnosed in 1991. I’m 56. I’ve been at my university for about as long as I’ve been bipolar. Why is it so hard to be a bipolar teacher in the higher education system?  The main reason is the stigma of the disease. As you probably know, even in 2019, there is horrible stigma about bipolar illness. There is sympathy for ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar College Personal Stigma Bipolar Disorder Depression Depressive Episode Manic Episode Teaching Source Type: blogs
Conclusion: Our results indicate similar prevalence rates of comorbid psychiatric symptoms to studies carried out in the Middle East and North Africa (MENA) region and relatively high attendance and referral rates to psychiatric services.Implications: The results shed light on the clinical profile of patients in this region and support the need for integrated collaborative medical services. Moreover, findings have important implications for health care policies pertaining to resource distribution and funding.IntroductionMedical care has traditionally been dominated by a separation between disciplines catering to physiologi...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Altered Brain Function in Drug-Naïve Major Depressive Disorder Patients With Early-Life Maltreatment: A Resting-State fMRI StudyZhexue Xu1,2†, Jing Zhang1†, Di Wang3†, Ting Wang4, Shu Zhang5, Xi Ren2, Xiaolei Zhu7, Atsushi Kamiya7, Jiliang Fang6* and Miao Qu1,2*1Department of Neurology, Xuan Wu Hospital Capital Medical University, Beijing, China2Department of Neurology, Third Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, China3Department of Clinical Psychology, Beijing Anding Hospital, Beijing, China4Nanjing Municipal Hospital of Traditional Chinese Medicine, Nanjing, China...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
ConclusionsSocial interactions are the most complex and ambiguous environments human beings place themselves in. Many explicit and implicit “rules” govern what is considered appropriate and what can be expected from any one interaction. Consequently, they are settings rife for miscommunication and misunderstanding. It requires intricate examination to determine exactly what the rewarding components of social interactions are. Social interactions are highly dynamic, complex circumstances that seem more inclined to produce anxiety than lead to rewards given their ambiguities. For those with social anhedonia, whos...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
 Most of us are familiar with post-traumatic stress disorder. PTSD (deservedly) gets a lot of attention, largely focused on soldiers returning from service. But trauma comes in many forms, and most people have experienced it in one form or another. In this episode, learn about the differences between PTSD and other forms of trauma, how to identify it, and what can be done about it.   Subscribe to Our Show! And Remember to Review Us! About Our Guest Robert T. Muller, Ph.D., is the author of the psychotherapy book, “Trauma &the Struggle to Open Up:  From Avoidance to Recovery &a...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General PTSD The Psych Central Show Trauma Gabe Howard Vincent M. Wales Source Type: blogs
Conclusion: Although a cause–effect relationship cannot be firmly stated, an association between early trauma experience and cognitive impairment such as visual memory, as well as a relationship between negative symptoms and attention domains, is suggested by our preliminary findings. Future studies with larger sample sizes and prospective design will clarify the long-term effects of early exposure to trauma and its clinical meaning in terms of developing psychotic-related illness.IntroductionMore than 75% of patients with schizophrenia show some level of cognitive impairment, leading to poor functional status and im...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
In this study, using multiple linear regression analysis, we found that decreased emotion coping appraisal of resilience in young adults was explained by an increased tendency to update beliefs about cue–outcome associative probability in a volatile environment and the increase in the parental verbal abuse experienced in early childhood. The total scores of resilience appraisals were also explained in the same manner (see Supplementary Tables 4 and 7). In addition, we did not find any effect of gender on the results both with whole subject (Figure 4) and in the gender-matched subgroup (see Supplementary Figure 3).Not...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
More News: Anxiety | Bipolar | Brain | Depression | Drugs & Pharmacology | Mania | Neurology | Post Traumatic Stress Disorder | Study