Mismatch repair prefers exons

Nature Genetics 49, 1673 (2017). doi:10.1038/ng.3993 Authors: Dashiell J Massey & Amnon Koren A new analysis of cancer genomes identifies a decrease in the mutation burden of exons, but not introns, as compared to expectation. This difference can be explained by preferential recruitment of the DNA mismatch repair machinery to a protein modification that marks exons.
Source: Nature Genetics - Category: Genetics & Stem Cells Authors: Tags: News and Views Source Type: research