Mammospheres of hormonal receptor positive breast cancer diverge to triple-negative phenotype.

CONCLUSIONS: Loss of HR and P53 expression in HR-positive mammospheres evidences the minor population of CSC which shares characteristics with the TNBC phenotype.
PMID: 29182983 [PubMed - as supplied by publisher]

Source: Breast - November 25, 2017 Category: Cancer & Oncology Authors: Laranjo M, Carvalho MJ, Costa T, Alves A, Oliveira RC, Casalta-Lopes J, Cordeiro P, Botas F, Abrantes AM, Paiva A, Oliveira C, Botelho MF Tags: Breast Source Type: research