The MTHFR polymorphism affect the susceptibility of HCC and the prognosis of HCC liver transplantation

ConclusionThis study demonstrated that MTHFR polymorphism was associated with HCC occurrence and post-transplant HCC recurrence. rs1801131 mutation A to C is a valuable molecular biomarker for predicting HCC occurrence in Chinese Han population. Donor MTHFR rs1801133 C to T polymorphism could present as a promising prognostic biomarkers for HCC recurrence in liver transplant recipients.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research