Correlates of Pulmonary Function in Children with Sickle Cell Disease and Elevated Fetal Hemoglobin

Conclusions: In this study, changes in PFT, especially FEV1, develop early in the SCD patients. There was no demonstrable association with frequent vaso-occlusive crisis, acute chest syndrome (ACS) and other variables. Hence, there is a need for follow up studies with serial PFTs to identify vulnerable patients, who might need intervention to prevent early mortality.
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research