Resveratrol promotes the arcuate nucleus architecture remodeling to produce more anorexigenic neurons in high fat diet fed mice

Over the past decades, there has been a dramatic increase in obesity all over the world (Hurt, Kulisek et  al. 2010). The epidemic rise of obesity and its associated comorbidities, including diabetes mellitus, hyperlipidemia, hypertension, cardiovascular diseases, and many forms of cancer, demonstrate the necessity to discover the molecular mechanisms underlying the onset of obesity (Hariri and Thibaul t 2010). In this sense, the increasing prevalence of obesity is partly due to the availability of energy-dense foods with a high fat (HF) content (Swinburn, Caterson et al.

Source: Nutrition - November 27, 2017 Category: Nutrition Authors: Maryam Safahani, Hadi Aligholi, Farshid Noorbakhsh, Mahmoud Djalali, Hamideh Pishva, Sayed Mostafa Modarres Mousavi, Fatemeh Alipour, Ali Gorji, Fariba Koohdani Source Type: research