Anti-citrullinated peptides antibodies in systemic sclerosis: meta-analysis of frequency and meaning

Conclusions The prevalence of ACPA in scleroderma is 9.2%. Our meta-analysis shows an increased risk for erosive arthritis, pulmonary fibrosis, oesophagus involvement and diffuse skin involvement, in patients with ACPA-positive SSc. ACPA should be systematically included in SSc assessment.
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research